Atypical teratoid rhabdoid tumor epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Atypical teratoid rhabdoid tumor comprises approximately 1–2% of all pediatric brain tumors; however, in patients less than 3 years of age, this tumor accounts for up to 20% of cases.[1] The incidence of atypical teratoid rhabdoid tumor is approximately 0.3 per 100,000 individuals in the United States.[2] Atypical teratoid rhabdoid tumor is a rare disease that tends to affect the children population.[3][4] The median age at diagnosis is approximately 24-30 months.[5] Males are more commonly affected with atypical teratoid rhabdoid tumor than females. The male to female ratio is approximately 1.9 to 1.[1]

Epidemiology and Demographics

Prevalence

  • Atypical teratoid rhabdoid tumor comprises approximately 1–2% of all pediatric brain tumors; however, in patients less than 3 years of age, this tumor accounts for up to 20% of cases.[1]

Incidence

  • The incidence of atypical teratoid rhabdoid tumor is approximately 0.3 per 100,000 individuals in the United States.[2]

Age

  • Atypical teratoid rhabdoid tumor is a rare disease that tends to affect the children population.[3][4]
  • However, although rare, atypical teratoid rhabdoid tumor has also been reported in adult patients.[6]
  • The median age at diagnosis is approximately 24-30 months.[5]

Gender

  • Males are more commonly affected with atypical teratoid rhabdoid tumor than females. The male to female ratio is approximately 1.9 to 1.[1]

References

  1. 1.0 1.1 1.2 1.3 Ginn, Kevin F.; Gajjar, Amar (2012). "Atypical Teratoid Rhabdoid Tumor: Current Therapy and Future Directions". Frontiers in Oncology. 2. ISSN 2234-943X. doi:10.3389/fonc.2012.00114. 
  2. 2.0 2.1 Atypical teratoid rhabdoid tumor. Wikipedia 2015. https://en.wikipedia.org/wiki/Atypical_teratoid_rhabdoid_tumor. Accessed on December 10, 2015
  3. 3.0 3.1 Epidemiology of atypical teratoid rhabdoid tumor. Dr Bruno Di Muzio and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/atypical-teratoidrhabdoid-tumour. Accessed on December 10, 2015
  4. 4.0 4.1 Clinical presentation of atypical teratoid rhabdoid tumor. National Cancer Institute 2015. http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq#link/_113_toc. Accessed on December 16, 2015
  5. 5.0 5.1 Slavc, Irene; Chocholous, Monika; Leiss, Ulrike; Haberler, Christine; Peyrl, Andreas; Azizi, Amedeo A.; Dieckmann, Karin; Woehrer, Adelheid; Peters, Christina; Widhalm, Georg; Dorfer, Christian; Czech, Thomas (2014). "Atypical teratoid rhabdoid tumor: improved long-term survival with an intensive multimodal therapy and delayed radiotherapy. The Medical University of Vienna Experience 1992-2012". Cancer Medicine. 3 (1): 91–100. ISSN 2045-7634. doi:10.1002/cam4.161. 
  6. Udaka, Y. T.; Shayan, K.; Chuang, N. A.; Crawford, J. R. (2013). "Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child". Case Reports in Oncological Medicine. 2013: 1–4. ISSN 2090-6706. doi:10.1155/2013/815923. 

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