Area postrema
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| Brain: Area postrema | ||
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| Rhomboid fossa. (Area postrema labeled at bottom center.) | ||
| Gray's | subject #187 800 | |
| Acronym(s) | AP | |
| NeuroNames | hier-769 | |
| MeSH | Area+postrema | |
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US National Guidelines Clearinghouse on Area postrema NICE Guidance on Area postrema
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Overview
The area postrema is a part of the brain that controls vomiting. It was discovered in 1953 by Utah Pharmacologists Herbert L. Borison and S. C. Wang [2].
Location
It is located in the lateral reticular formation of the medulla oblongata. More specifically, it is located between the funiculus separans (a narrow translucent ridge cossing the ala cinerea) and the clava, as a small tongue-shaped area.
Function
The Area postrema, one of the circumventricular organs, detects toxins in the blood and acts as a vomit inducing center. It connects to the Nucleus of the Solitary Tract and other autonomic control centres in the brainstem. It is thus excited by visceral afferent impulses (sympathetic and vagal) arising from the gastrointestinal tract and other peripheral trigger areas.
External links
de:BrechzentrumAcknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
