Angiomyolipoma risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2], Rekha, M.D.

Overview

Tuberous sclerosis is a risk factor for the development of angiomyolipoma. Approximately 50% of individuals with tuberous sclerosis develop bilateral angiomyolipomas.

The most potent risk factor for the development of angiomyolipoma includes:^[1]^[2]^[3]^[4]
- Tuberous sclerosis
  - Approximately 50% of individuals with tuberous sclerosis develop bilateral angiomyolipomas.
- Genetic mutations

↑ Ewalt DH, Sheffield E, Sparagana SP, Delgado MR, Roach ES (1998). "Renal lesion growth in children with tuberous sclerosis complex". J Urol. 160 (1): 141–5. PMID 9628635.
↑ Casper KA, Donnelly LF, Chen B, Bissler JJ (2002). "Tuberous sclerosis complex: renal imaging findings". Radiology. 225 (2): 451–6. doi:10.1148/radiol.2252011584. PMID 12409579.
↑ Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA (2006). "Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors". Kidney Int. 70 (10): 1777–82. doi:10.1038/sj.ki.5001853. PMID 17003820.
↑ Ewalt DH, Sheffield E, Sparagana SP, Delgado MR, Roach ES (1998). "Renal lesion growth in children with tuberous sclerosis complex". J Urol. 160 (1): 141–5. PMID 9628635.