Cefazolin

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Image:Cefazolin.png
Cefazolin
Systematic (IUPAC) name
3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]- 8-oxo-7-([2-(tetrazol-1-yl)acetyl]amino)- 5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate
Identifiers
CAS number	25953-19-9
ATC code	J01DB04
PubChem	33255
Chemical data
Formula	C14H13N8O4S3
Mol. mass	454.51 g/mol
Pharmacokinetic data
Bioavailability	NA
Metabolism	?
Half life	1.8 hours (given IV) 2 hours (given IM)
Excretion	Renal, unchanged
Therapeutic considerations
Pregnancy cat.	B1(AU) B(US)
Legal status	℞ Prescription only
Routes	Intravenous, intramuscular

WikiDoc Resources for Cefazolin
Articles
Most recent articles on Cefazolin Most cited articles on Cefazolin Review articles on Cefazolin Articles on Cefazolin in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Cefazolin Images of Cefazolin Photos of Cefazolin Podcasts & MP3s on Cefazolin Videos on Cefazolin
Evidence Based Medicine
Cochrane Collaboration on Cefazolin Bandolier on Cefazolin TRIP on Cefazolin
Clinical Trials
Ongoing Trials on Cefazolin at Clinical Trials.gov Trial results on Cefazolin Clinical Trials on Cefazolin at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Cefazolin NICE Guidance on Cefazolin NHS PRODIGY Guidance FDA on Cefazolin CDC on Cefazolin
Books
Books on Cefazolin
News
Cefazolin in the news Be alerted to news on Cefazolin News trends on Cefazolin
Commentary
Blogs on Cefazolin
Definitions
Definitions of Cefazolin
Patient Resources / Community
Patient resources on Cefazolin Discussion groups on Cefazolin Patient Handouts on Cefazolin Directions to Hospitals Treating Cefazolin Risk calculators and risk factors for Cefazolin
Healthcare Provider Resources
Symptoms of Cefazolin Causes & Risk Factors for Cefazolin Diagnostic studies for Cefazolin Treatment of Cefazolin
Continuing Medical Education (CME)
CME Programs on Cefazolin
International
Cefazolin en Espanol Cefazolin en Francais
Businness
Cefazolin in the Marketplace Patents on Cefazolin
Experimental / Informatics
List of terms related to Cefazolin

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Cefazolin (INN), also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic.

The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein).

Indications

Cefazolin is mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. These organisms are common on normal human skin. Resistance to cefazolin is seen in several species of bacteria.

Side effects

Side effects from cefazolin are not common. Possible side effects include:

• diarrhea
• stomach pain
• upset stomach
• vomiting

Cefazolin is marketed under the following brand names: Ancef®, Cefacidal®, Cefamezin®, Cefrina®, Elzogram®, Faxilen®, Gramaxin®, Kefazol®, Kefol®, Kefzol®, Kefzolan®, Kezolin®, Novaporin®, and Zolicef®

External links

• MedlinePlus Drug Information: Cefazolin Sodium Injection.
• Eli Lilly Cefazolin Sodium Material Safety Data Sheet.

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D)
First generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second generation	Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime
Third generation	Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef
Fourth generation	Cefepime, Cefpirome, Cefquinome
Fifth generation	Ceftobiprole
Other beta-lactam antibacterials	Monobactams (Aztreonam), Carbapenems (Parenteral - Meropenem, Ertapenem, Imipenem, Doripenem, Oral - Faropenem)

v • d • e WikiDoc Research Resources for Cefazolin (Click show to right to view)
Articles on Cefazolin	Most recent articles on Cefazolin • Most cited articles on Cefazolin • Review articles on Cefazolin • Articles on Cefazolin in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Cefazolin	Powerpoint slides on Cefazolin • Images of Cefazolin • Photos of Cefazolin • Podcasts & MP3s on Cefazolin • Videos on Cefazolin
Evidence Based Medicine Regarding Cefazolin	Cochrane Collaboration on Cefazolin • Bandolier on Cefazolin • TRIP on Cefazolin
Cost Effectiveness of Cefazolin	Cost Effectiveness of Cefazolin
Clinical Trials Involving Cefazolin	Ongoing Trials on Cefazolin at Clinical Trials.gov • Trial results on Cefazolin • Clinical Trials on Cefazolin at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Cefazolin	US National Guidelines Clearinghouse on Cefazolin • NICE Guidance on Cefazolin • NHS PRODIGY Guidance • FDA on Cefazolin • CDC on Cefazolin
Textbook Information on Cefazolin	Books and Textbook Information on Cefazolin
Pharmacology Resources on Cefazolin	Dosing of Cefazolin • Drug interactions with Cefazolin • Side effects of Cefazolin • Allergic reactions to Cefazolin • Overdose information on Cefazolin • Carcinogenicity information on Cefazolin • Cefazolin in pregnancy • Pharmacokinetics of Cefazolin •
Genetics, Pharmacogenomics, and Proteinomics of Cefazolin	Genetics of Cefazolin • Pharmacogenomics of Cefazolin • Proteomics of Cefazolin
Newstories on Cefazolin	Cefazolin in the news • Be alerted to news on Cefazolin • News trends on Cefazolin
Commentary on Cefazolin	Blogs on Cefazolin
Patient Resources on Cefazolin	Patient resources on Cefazolin • Discussion groups on Cefazolin • Patient Handouts on Cefazolin • Directions to Hospitals Treating Cefazolin • Risk calculators and risk factors for Cefazolin
Healthcare Provider Resources on Cefazolin	Symptoms of Cefazolin • Causes & Risk Factors for Cefazolin • Diagnostic studies for Cefazolin • Treatment of Cefazolin
Continuing Medical Education (CME) Programs on Cefazolin	CME Programs on Cefazolin
International Resources on Cefazolin	Cefazolin en Espanol • Cefazolin en Francais
Business Resources on Cefazolin	Cefazolin in the Marketplace • Patents on Cefazolin
Informatics Resources on Cefazolin	List of terms related to Cefazolin

fr:Céfazolineth:เซฟาโซลิน de:Cefazolin

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .