Anal cancer epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [3]

Overview

In 2008-2012, the incidence of anal cancer was estimated to be 1.8 cases per 100,000 individuals in the US.

Epidemiology

Incidence[1]

  • In women and men who do not engage in anal intercourse with other men - 0.9/100,000
  • In HIV negative men who engage in anal intercourse with other men - 35/100,000
  • In HIV positive men who engage in anal intercourse with other men - (estimated) 60-70/100,000
  • Number of New Cases and Deaths per 100,000: The number of new cases of anal cancer was 1.8 per 100,000 men and women per year. The number of deaths was 0.2 per 100,000 men and women per year. These rates are age-adjusted and based on 2008-2012 cases and deaths.
  • Lifetime Risk of Developing Cancer: Approximately 0.2 percent of men and women will be diagnosed with anal cancer at some point during their lifetime, based on 2010-2012 data.[2]
  • Because it is rare and because it occurs in a body part that is rarely discussed, most people are unaware of its existence.
An examination of squamous cell carcinoma tumor tissues from patients in Denmark and Sweden showed a high proportion of anal cancers to be positive for the types of HPV that are also associated with high risk of cervical cancer (90% of the tumors from women, 100% of the tumors from homosexual men, and 58% of tumors from heterosexual men).[3]

References

  1. Anal Carcinoma [1]
  2. National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015.http://seer.cancer.gov/statfacts/html/anus.html
  3. Danish Medical Bulletin. 2002 Aug;49(3):194-209