Alcoholic polyneuropathy

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Alcoholic polyneuropathy is a neurological disorder in which many peripheral nerves throughout the body malfunction simultaneously (a polyneuropathy). Alcoholic polyneuropathy usually has a gradual onset with usually more sensory than motor symptoms, usually with the involvement of legs more than the arms. There is usually symmetric sensory loss, and painful paresthesias, though all sensory modalities may be involved. Patients also see distal weakness, muscle wasting, and decreased or absent deep tendon reflexes.

Treatment includes vitamin supplementation (especially thiamine), nutritional support, NSAIDs, and tricyclic antidepressants (e.g., amitriptyline). Physiotherapy is also a part of treatment. Recovery is slow, and usually happens over weeks to months.

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Alcoholic Neuropathy

v • d • e Nervous system pathology, primarily PNS (G50-G99, 350-359)
Nerve, nerve root and plexus disorders (neuropathy, radiculopathy, plexopathy)	cranial nerve: V (Trigeminal neuralgia) - VII (Facial nerve paralysis, Bell's palsy, Melkersson-Rosenthal syndrome, Central seven) - XI (Accessory nerve disorder) nerve root and plexus: Brachial plexus lesion - Thoracic outlet syndrome - Phantom limb mononeuropathy: upper limb (Carpal tunnel syndrome, Ulnar nerve entrapment, Radial neuropathy) - Causalgia - lower limb (Meralgia paraesthetica, Tarsal tunnel syndrome, Morton's neuroma) - Mononeuritis multiplex
Polyneuropathies and other disorders of the PNS	hereditary and idiopathic (Charcot-Marie-Tooth disease, Dejerine Sottas syndrome, Refsum's disease, Morvan's syndrome) Guillain-Barré syndrome - Alcoholic polyneuropathy
Diseases of myoneural junction	autoimmune: Myasthenia gravis - Lambert-Eaton myasthenic syndrome
Diseases of muscle (myopathy)	Muscular dystrophy myotonic (Myotonic dystrophy, Myotonia congenita, Thomsen disease, Neuromyotonia, Paramyotonia congenita) congenital myopathy (Centronuclear myopathy, Nemaline myopathy, Central core disease) Mitochondrial myopathy periodic paralysis: Hypokalemic - Hyperkalemic
Autonomic	Familial dysautonomia - Horner's syndrome - Multiple system atrophy (Shy-Drager syndrome, Olivopontocerebellar atrophy)