Adenosine-phosphate deaminase

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In enzymology, an adenosine-phosphate deaminase (EC 3.5.4.17) is an enzyme that catalyzes the chemical reaction

5'-AMP + H2O 5'-IMP + NH3

Thus, the two substrates of this enzyme are 5'-AMP and H2O, whereas its two products are 5'-IMP and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is adenosine-phosphate aminohydrolase. Other names in common use include adenylate deaminase, adenine nucleotide deaminase, and adenosine (phosphate) deaminase.

References

  • IUBMB entry for 3.5.4.17
  • BRENDA references for 3.5.4.17 (Recommended.)
  • PubMed references for 3.5.4.17
  • PubMed Central references for 3.5.4.17
  • Google Scholar references for 3.5.4.17
  • Su JC, Li CC, Ting CC (1966). "A new adenylate deaminase from red marine alga Porphyra crispata". Biochemistry. 5: 536&ndash, 43. PMID 5940938.
  • Yates MG (1969). "A non-specific adenine nucleotide deaminase from desulfovibrio desulfuricans". Biochim. Biophys. Acta. 171: 299&ndash, 310. PMID 5773435.

External links

The CAS registry number for this enzyme class is 37289-20-6.

Gene Ontology (GO) codes


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