Acetylpyruvate hydrolase

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In enzymology, an acetylpyruvate hydrolase (EC is an enzyme that catalyzes the chemical reaction

acetylpyruvate + H2O acetate + pyruvate

Thus, the two substrates of this enzyme are acetylpyruvate and H2O, whereas its two products are acetate and pyruvate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2,4-dioxopentanoate acetylhydrolase.


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  • Davey JF, Ribbons DW (1975). "Metabolism of resorcinylic compounds by bacteria. Purification and properties of acetylpyruvate hydrolase from Pseudomonas putida 01". J. Biol. Chem. 250: 3826&ndash, 30. PMID 236305.

External links

The CAS registry number for this enzyme class is 56214-30-3.

Gene Ontology (GO) codes