6-aminohexanoate-dimer hydrolase

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In enzymology, a 6-aminohexanoate-dimer hydrolase (EC is an enzyme that catalyzes the chemical reaction

N-(6-aminohexanoyl)-6-aminohexanoate + H2O 2 6-aminohexanoate

Thus, the two substrates of this enzyme are N-(6-aminohexanoyl)-6-aminohexanoate and H2O, whereas its product is 6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase. This enzyme is also called 6-aminohexanoic acid oligomer hydrolase.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1WYB, 1WYC, and 2DCF.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Okada H (1981). "Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72". Eur. J. Biochem. 116: 547&ndash, 51. PMID 7262074.

External links

The CAS registry number for this enzyme class is 75216-15-8.

Gene Ontology (GO) codes