(pyruvate kinase)-phosphatase

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In enzymology, a [pyruvate kinase]-phosphatase (EC is an enzyme that catalyzes the chemical reaction

[pyruvate kinase] phosphate + H2O [pyruvate kinase] + phosphate

Thus, the two substrates of this enzyme are [[[pyruvate kinase] phosphate]] and H2O, whereas its two products are pyruvate kinase and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is [ATP:pyruvate 2-O-phosphotransferase]-phosphate phosphohydrolase. This enzyme is also called pyruvate kinase phosphatase.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
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  • Google Scholar references for
  • Jett MF, Hue L, Hers HG (1981). "Pyruvate kinase phosphatase". FEBS. Lett. 132: 183&ndash, 6. PMID 6271587.

External links

The CAS registry number for this enzyme class is 79986-25-7.

Gene Ontology (GO) codes