Zinc finger protein 165: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Zinc finger protein 165''' is a [[protein]] that in humans is encoded by the ''ZNF165'' [[gene]].<ref name="pmid7490084">{{cite journal | vauthors = Tirosvoutis KN, Divane A, Jones M, Affara NA | title = Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis | journal = Genomics | volume = 28 | issue = 3 | pages = 485–90 | date = Jan 1996 | pmid = 7490084 | pmc =  | doi = 10.1006/geno.1995.1178 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ZNF165 zinc finger protein 165| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7718| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Zinc finger protein 165
| HGNCid = 12953
| Symbol = ZNF165
| AltSymbols =; LD65; ZSCAN7
| OMIM = 600834
| ECnumber = 
| Homologene = 48191
| MGIid = 
| GeneAtlas_image1 = PBB_GE_ZNF165_206683_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7718
    | Hs_Ensembl = ENSG00000197279
    | Hs_RefseqProtein = NP_003438
    | Hs_RefseqmRNA = NM_003447
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 28154551
    | Hs_GenLoc_end = 28165320
    | Hs_Uniprot = P49910
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Zinc finger protein 165''', also known as '''ZNF165''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZNF165 zinc finger protein 165| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7718| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.<ref name="entrez">{{cite web | title = Entrez Gene: ZNF165 zinc finger protein 165| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7718| accessdate = }}</ref>
}}


==See also==
== Interactions ==
 
Zinc finger protein 165 has been shown to [[Protein–protein interaction|interact]] with [[Ewing sarcoma breakpoint region 1]]<ref name=pmid16189514>{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein–protein interaction network| authorlink30=Huda Zoghbi | journal = [[Nature (journal)|Nature]] | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}</ref> and [[DVL2]].<ref name=pmid16189514/>
 
== See also ==
* [[Zinc finger]]
* [[Zinc finger]]


==References==
== References ==
{{reflist|2}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Lee PL, Gelbart T, West C, Adams M, Blackstone R, Beutler E | title = Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. | journal = Genomics | volume = 43 | issue = 2 | pages = 191–201 | year = 1997 | pmid = 9244436 | doi = 10.1006/geno.1997.4806 }}
| citations =
* {{cite journal | vauthors = Paoloni-Giacobino A, Kern I, Rumpler Y, Djlelati R, Morris MA, Dahoun SP | title = Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility. | journal = Clin. Genet. | volume = 58 | issue = 4 | pages = 324–8 | year = 2001 | pmid = 11076058 | doi = 10.1034/j.1399-0004.2000.580411.x }}
*{{cite journal | author=Tirosvoutis KN, Divane A, Jones M, Affara NA |title=Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis. |journal=Genomics |volume=28 |issue= 3 |pages= 485-90 |year= 1996 |pmid= 7490084 |doi= 10.1006/geno.1995.1178 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein–protein interaction network. | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal  | author=Lee PL, Gelbart T, West C, ''et al.'' |title=Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. |journal=Genomics |volume=43 |issue= 2 |pages= 191-201 |year= 1997 |pmid= 9244436 |doi= 10.1006/geno.1997.4806 }}
*{{cite journal | author=Paoloni-Giacobino A, Kern I, Rumpler Y, ''et al.'' |title=Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility. |journal=Clin. Genet. |volume=58 |issue= 4 |pages= 324-8 |year= 2001 |pmid= 11076058 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
{{refend}}
{{refend}}


== External links ==
== External links ==
* {{MeshName|ZNF165+protein,+human}}
* {{MeshName|ZNF165+protein,+human}}
{{Transcription factors|g2}}


{{NLM content}}
{{NLM content}}
{{protein-stub}}
 
{{Transcription factors}}
[[Category:Transcription factors]]
[[Category:Transcription factors]]
{{WikiDoc Sources}}
 
 
{{gene-6-stub}}

Latest revision as of 02:15, 27 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene.[1][2]

Function

This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.[2]

Interactions

Zinc finger protein 165 has been shown to interact with Ewing sarcoma breakpoint region 1[3] and DVL2.[3]

See also

References

  1. ↑ Tirosvoutis KN, Divane A, Jones M, Affara NA (Jan 1996). "Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis". Genomics. 28 (3): 485–90. doi:10.1006/geno.1995.1178. PMID 7490084.
  2. ↑ 2.0 2.1 "Entrez Gene: ZNF165 zinc finger protein 165".
  3. ↑ 3.0 3.1 Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

  • Lee PL, Gelbart T, West C, Adams M, Blackstone R, Beutler E (1997). "Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain". Genomics. 43 (2): 191–201. doi:10.1006/geno.1997.4806. PMID 9244436.
  • Paoloni-Giacobino A, Kern I, Rumpler Y, Djlelati R, Morris MA, Dahoun SP (2001). "Familial t(6;21)(p21.1;p13) translocation associated with male-only sterility". Clin. Genet. 58 (4): 324–8. doi:10.1034/j.1399-0004.2000.580411.x. PMID 11076058.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein–protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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