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Synonyms / Brand Names: Bisoprolol Fumarate, Bisoprolol fumerate, Bisoprolol Hemifumarate, Cardicor, Concor, Condyline, Detensiel, Emconcor, Emcor, Euradal, Isoten, Monocor, Soloc, Soprol, Zebeta

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

Bisoprolol is an effective treatment of hypertension in once-daily doses of 2.5 to 40 mg, while hydrochlorothiazide is effective in doses of 12.5 to 50 mg. In clinical trials of bisoprolol/hydrochlorothiazide combination therapy using bisoprolol doses of 2.5 to 20 mg and hydrochlorothiazide doses of 6.25 to 25 mg, the antihypertensive effects increased with increasing doses of either component.

FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español

FDA Package Insert Resources



Side Effects

Drug Interactions



Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA label

FDA on Ziac

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Publication Resources

Most Recent Articles on Ziac

Review Articles on Ziac

Articles on Ziac in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Ziac

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Trial Resources

Ongoing Trials with Ziac at Clinical Trials.gov

Trial Results with Ziac

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Ziac

Cochrane Collaboration on Ziac

Cost Effectiveness of Ziac

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Media Resources

Powerpoint Slides on Ziac

Images of Ziac

Podcasts & MP3s on Ziac

Videos on Ziac

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Patient Resources

Patient Information from National Library of Medicine

Patient Resources on Ziac

Discussion Groups on Ziac

Patient Handouts on Ziac

Blogs on Ziac

Ziac in the News

Ziac in the Marketplace

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International Resources

Ziac en Español

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Adapted from the FDA Package Insert.