Zazam Sheriff Phillips syndrome

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Overview

Zazam Sheriff Phillips syndrome is a rare[1] genetically congenital syndrome. It is associated with the symptoms of Aniridia, ectopia lentis, abnormal upper incisors and mental retardation.[2]

It is believed to be inherited in an autosomal recessive fashion. Not a lot of research has been undertaken of this particular disease so thus far there is no known gene that affects this condition. However it has been hypothesised that the symptoms described are found at a particular gene, though mental retardation is believed to be due to a different genetic cause.

Consanguinuity has been attributed to affect the chances of inheriting this disease.[3]

References

  1. Template:RareDiseases
  2. Birth Disorder Information Directory - Z
  3. Zamzam AM, Sheriff SM, Phillips CI (1988). "Aniridia, ectopia lentis, abnormal upper incisors and mental retardation--an autosomal recessive syndrome". Jpn. J. Ophthalmol. 32 (4): 375–8. PMID 3266265.


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