ZMPSTE24

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zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Identifiers
Symbol	ZMPSTE24
Entrez	10269
HUGO	12877
OMIM	606480
RefSeq	NM_005857
UniProt	O75844
Other data
EC number	3.4.24.84
Locus	Chr. 1 p34

ZMPSTE24 is a human gene.^[1]^[2] The protein encoded by this gene is a metallopeptidase. It is involved in the processing of Lamin A.^[3]

References

↑ Tam A, Nouvet FJ, Fujimura-Kamada K, Slunt H, Sisodia SS, Michaelis S (1998). "Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing". J. Cell Biol. 142 (3): 635–49. PMC 2148179. PMID 9700155. Unknown parameter |month= ignored (help)
↑ Freije JM, Blay P, Pendás AM, Cadiñanos J, Crespo P, López-Otín C (1999). "Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins". Genomics. 58 (3): 270–80. doi:10.1006/geno.1999.5834. PMID 10373325. Unknown parameter |month= ignored (help)
↑ Young SG, Fong LG, Michaelis S (2005). "Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis". J. Lipid Res. 46 (12): 2531–58. doi:10.1194/jlr.R500011-JLR200. PMID 16207929. Unknown parameter |month= ignored (help)