Waldenström's macroglobulinemia physical examination: Difference between revisions
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===General Appearance=== | ===General Appearance=== | ||
Patients with Waldenström macroglobulinemia are generally well appearing.<ref name="aa">Waldenström's macroglobulinemia. MedlinePlus (2015) https://www.nlm.nih.gov/medlineplus/ency/article/000588.htm Accessed on November 15th, 2015</ref> | Patients with Waldenström macroglobulinemia are generally well-appearing.<ref name="aa">Waldenström's macroglobulinemia. MedlinePlus (2015) https://www.nlm.nih.gov/medlineplus/ency/article/000588.htm Accessed on November 15th, 2015</ref> | ||
===Skin=== | ===Skin=== | ||
*[[Purpura]] | *[[Purpura]] | ||
*[[Raynaud phenomenon]] | *[[Raynaud phenomenon]] | ||
*[[Petechiae]] if platelet count is low | *[[Petechiae]] - if platelet count is low | ||
===HEENT=== | ===HEENT=== | ||
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===Cardiovascular system=== | ===Cardiovascular system=== | ||
*Displaced apical impulse | *[[Apical impulse|Displaced apical impulse]] | ||
*[[S3 gallop]] | *[[S3 gallop]] | ||
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===Extremity=== | ===Extremity=== | ||
*[[Raynaud phenomenon]] | *[[Raynaud phenomenon]] | ||
*Patients may have peripheral edema if disease is complicated by [[congestive heart failure]]. | *Patients may have [[peripheral edema]] if disease is complicated by [[congestive heart failure]]. | ||
===Neuromuscular=== | ===Neuromuscular=== | ||
*[[Peripheral neuropathy]] | *[[Peripheral neuropathy]] - distal, symmetric, and sensorimotor<ref name="cns">{{cite journal |vauthors=Coimbra J, Costa AP, Pita F, Rosado P, de Almeida LB |title=[Neuropathy in Waldenstrom's macroglobulinemia] |language=Portuguese |journal=Acta Med Port |volume=8 |issue=4 |pages=253–7 |year=1995 |pmid=7625222 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
Revision as of 20:11, 23 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]
Overview
Patients with Waldenström macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with Waldenström's macroglobulinemia is usually remarkable for various findings depending on the degree of tissue infiltration by malignant tumor cells, hyperviscosity syndrome, and accumulation of paraprotein.
Physical Examination
General Appearance
Patients with Waldenström macroglobulinemia are generally well-appearing.[1]
Skin
- Purpura
- Raynaud phenomenon
- Petechiae - if platelet count is low
HEENT
Neck
Respiratory
- Pleural effusion - in 3-5% of patients
- Rales on auscultation
Cardiovascular system
Abdomen
Extremity
- Raynaud phenomenon
- Patients may have peripheral edema if disease is complicated by congestive heart failure.
Neuromuscular
- Peripheral neuropathy - distal, symmetric, and sensorimotor[2]
References
- ↑ Waldenström's macroglobulinemia. MedlinePlus (2015) https://www.nlm.nih.gov/medlineplus/ency/article/000588.htm Accessed on November 15th, 2015
- ↑ Coimbra J, Costa AP, Pita F, Rosado P, de Almeida LB (1995). "[Neuropathy in Waldenstrom's macroglobulinemia]". Acta Med Port (in Portuguese). 8 (4): 253–7. PMID 7625222.