Viral meningitis laboratory findings: Difference between revisions

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==Laboratory findings==
==Laboratory findings==
===Non specific tests===
====Blood tests====
It is performed routinely to any suspected meningitis patients. It includes the following:
*CBC
*Blood culture
*PT and PTT
*Glucose level
*Creatine level
====Different tissue samples====
Samples can be taken by different ways from the suspected meningitis patients.They may be collected for testing by:<ref name= "Viral meningitis"> CDC https://www.cdc.gov/meningitis/viral.html Accessed on April 20, 2017 </ref>
*Nose swabbing
*Throat swabbing
*Rectum swabbing
*Taking a stool sample
*Drawing fluid from around your spinal cord.
===Specific tests===
===Specific tests===
Specific diagnostic tests include [[lumbar puncture]] with CSF examination and CSF culture. CSF examination findings in bacterial meningitis are as follows:
Specific diagnostic tests include [[lumbar puncture]] with CSF examination. CSF examination findings in viral meningitis are as follows:
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Revision as of 17:48, 20 April 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Laboratory findings

Non specific tests

Blood tests

It is performed routinely to any suspected meningitis patients. It includes the following:

  • CBC
  • Blood culture
  • PT and PTT
  • Glucose level
  • Creatine level

Different tissue samples

Samples can be taken by different ways from the suspected meningitis patients.They may be collected for testing by:[1]

  • Nose swabbing
  • Throat swabbing
  • Rectum swabbing
  • Taking a stool sample
  • Drawing fluid from around your spinal cord.

Specific tests

Specific diagnostic tests include lumbar puncture with CSF examination. CSF examination findings in viral meningitis are as follows:

Cerebrospinal fluid level Normal level Viral meningitis[2]
Cells/ul < 5 >100
Cells Lymphos:Monos 7:3 Lymphocytes>granulocytes
Total protein (mg/dl) 45-60 Normal or slightly elevated
Glucose ratio (CSF/plasma)[3] > 0.5 >0.6
Lactate (mmols/l)[4] < 2.1 < 2.1
Others ICP:6-12 (cm H2O) Throat swap

References

  1. CDC https://www.cdc.gov/meningitis/viral.html Accessed on April 20, 2017
  2. Negrini B, Kelleher KJ, Wald ER (2000). "Cerebrospinal fluid findings in aseptic versus bacterial meningitis". Pediatrics. 105 (2): 316–9. PMID 10654948.
  3. Chow E, Troy SB (2014). "The differential diagnosis of hypoglycorrhachia in adult patients". Am J Med Sci. 348 (3): 186–90. doi:10.1097/MAJ.0000000000000217. PMC 4065645. PMID 24326618.
  4. Leen WG, Willemsen MA, Wevers RA, Verbeek MM (2012). "Cerebrospinal fluid glucose and lactate: age-specific reference values and implications for clinical practice". PLoS One. 7 (8): e42745. doi:10.1371/journal.pone.0042745. PMC 3412827. PMID 22880096.