Viral meningitis laboratory findings: Difference between revisions
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(Created page with "__NOTOC__ {{Viral meningitis}} {{CMG}}{{AE}}{{AEL}} ==Overview== ==Laboratory findings== ==References== {{Reflist|2}}") |
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==Overview== | ==Overview== | ||
==Laboratory findings== | ==Laboratory findings== | ||
===Specific tests=== | |||
Specific diagnostic tests include [[lumbar puncture]] with CSF examination and CSF culture. CSF examination findings in bacterial meningitis are as follows: | |||
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center | |||
|+ | |||
! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Cerebrospinal fluid level}} | |||
! style="background: #4479BA; width: 350px;" | {{fontcolor|#FFF|Normal level}} | |||
! style="background: #4479BA; width: 350px;" | {{fontcolor|#FFF|Bacterial meningitis}}<ref name="pmid10654948">{{cite journal| author=Negrini B, Kelleher KJ, Wald ER| title=Cerebrospinal fluid findings in aseptic versus bacterial meningitis. | journal=Pediatrics | year= 2000 | volume= 105 | issue= 2 | pages= 316-9 | pmid=10654948 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10654948 }} </ref> | |||
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| style="padding: 5px 5px; background: #DCDCDC;" | '''Cells/ul''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''< 5''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''>300''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |'''Cells''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''Lymphos:Monos 7:3''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''Gran. > Lymph''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |'''Total protein (mg/dl''') | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''45-60''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''Typically 100-500''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |'''Glucose ratio (CSF/plasma)<ref name="pmid24326618">{{cite journal| author=Chow E, Troy SB| title=The differential diagnosis of hypoglycorrhachia in adult patients. | journal=Am J Med Sci | year= 2014 | volume= 348 | issue= 3 | pages= 186-90 | pmid=24326618 | doi=10.1097/MAJ.0000000000000217 | pmc=4065645 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24326618 }} </ref>''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''> 0.5''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''< 0.3''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |'''Lactate (mmols/l)<ref name="pmid22880096">{{cite journal| author=Leen WG, Willemsen MA, Wevers RA, Verbeek MM| title=Cerebrospinal fluid glucose and lactate: age-specific reference values and implications for clinical practice. | journal=PLoS One | year= 2012 | volume= 7 | issue= 8 | pages= e42745 | pmid=22880096 | doi=10.1371/journal.pone.0042745 | pmc=3412827 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22880096 }} </ref>''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''< 2.1''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''> 2.1''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |'''Others''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''ICP:6-12 (cm H2O)''' | |||
| style="padding: 5px 5px; background: #F5F5F5;" |'''CSF gram stain, CSF culture, CSF bacterial antigen''' | |||
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|} | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 17:09, 20 April 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Laboratory findings
Specific tests
Specific diagnostic tests include lumbar puncture with CSF examination and CSF culture. CSF examination findings in bacterial meningitis are as follows:
| Cerebrospinal fluid level | Normal level | Bacterial meningitis[1] |
|---|---|---|
| Cells/ul | < 5 | >300 |
| Cells | Lymphos:Monos 7:3 | Gran. > Lymph |
| Total protein (mg/dl) | 45-60 | Typically 100-500 |
| Glucose ratio (CSF/plasma)[2] | > 0.5 | < 0.3 |
| Lactate (mmols/l)[3] | < 2.1 | > 2.1 |
| Others | ICP:6-12 (cm H2O) | CSF gram stain, CSF culture, CSF bacterial antigen |
References
- ↑ Negrini B, Kelleher KJ, Wald ER (2000). "Cerebrospinal fluid findings in aseptic versus bacterial meningitis". Pediatrics. 105 (2): 316–9. PMID 10654948.
- ↑ Chow E, Troy SB (2014). "The differential diagnosis of hypoglycorrhachia in adult patients". Am J Med Sci. 348 (3): 186–90. doi:10.1097/MAJ.0000000000000217. PMC 4065645. PMID 24326618.
- ↑ Leen WG, Willemsen MA, Wevers RA, Verbeek MM (2012). "Cerebrospinal fluid glucose and lactate: age-specific reference values and implications for clinical practice". PLoS One. 7 (8): e42745. doi:10.1371/journal.pone.0042745. PMC 3412827. PMID 22880096.