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==Overview==
==Overview==
Vaginal cancer may be classified according to histopathology into [[squamous cell carcinoma]], [[adenocarcinoma]], vaginal [[germ cell tumor]], and vaginal sarcoma.  
Vaginal cancer may be classified according to histopathology into [[squamous cell carcinoma]], [[adenocarcinoma]], vaginal [[germ cell tumor]], and vaginal sarcoma.  


==Types of vaginal cancer==
==Types of vaginal cancer==
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* '''Vaginal [[adenocarcinoma]]: '''
* '''Vaginal [[adenocarcinoma]]: '''
:* Approximately 15%, second most common subtype, presents in younger individuals and arises from the glandular (secretory) cells in the lining of the vagina that produce some vaginal fluids. Adenocarcinoma is more likely than squamous cell cancer to spread to the [[lung]]s and [[lymph node]]s. The majority of cases of adneocarcinoma occur in women younger than 30 years and has been found in a small percentage of women whose mothers in the 1950s used [[diethylstilbestrol]] to prevent threatened abortions.
:* Approximately 15%, second most common subtype, presents in younger individuals and arises from the glandular (secretory) cells in the lining of the vagina that produce some vaginal fluids.  
:* Adenocarcinoma is more likely than squamous cell cancer to spread to the [[lung]]s and [[lymph node]]s.  
:* The majority of cases of adneocarcinoma occur in women younger than 30 years and has been found in a small percentage of women whose mothers in the 1950s used [[diethylstilbestrol]] to prevent threatened abortions.


::* Clear cell carcinoma of the vagina: rare, associated with previous [[diethylstilbestrol]] (DES) exposure
::* '''Clear cell carcinoma of the vagina:''' rare, associated with previous [[diethylstilbestrol]] (DES) exposure


* '''Vaginal [[germ cell tumor]]s: '''
* '''Vaginal [[germ cell tumor]]s: '''

Revision as of 15:23, 2 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Vaginal cancer may be classified according to histopathology into squamous cell carcinoma, adenocarcinoma, vaginal germ cell tumor, and vaginal sarcoma.

Types of vaginal cancer

Types of vaginal cancer, in order of prevalence, include:

  • Arises from the thin, flat squamous cells that line the vagina. By far the commonest, it accounts for 80-85% of primary vaginal malignancies and presents in older individuals.
  • Approximately 15%, second most common subtype, presents in younger individuals and arises from the glandular (secretory) cells in the lining of the vagina that produce some vaginal fluids.
  • Adenocarcinoma is more likely than squamous cell cancer to spread to the lungs and lymph nodes.
  • The majority of cases of adneocarcinoma occur in women younger than 30 years and has been found in a small percentage of women whose mothers in the 1950s used diethylstilbestrol to prevent threatened abortions.
  • Clear cell carcinoma of the vagina: rare, associated with previous diethylstilbestrol (DES) exposure
  • Vaginal sarcoma:

References