Undifferentiated connective tissue disease physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Physical Examination

• The presence of following findings on physical examination is highly suggestive of undifferentiated connective tissue disease(UCTD):

Appearance of the Patient

• Patients with UCTD usually appear [general appearance].

Vital Signs

• Low-grade fever

Skin

• Raynaud's phenomenon
• Rash
• Erythema nodosum

HEENT

• Conjunctivitis
• Uveitis
• Keratoconjunctivitis sicca
• Dry-mouth

Neck

• Lymphadenopathy (describe location, size, tenderness, mobility, and symmetry)

Lungs

• Rhonchi
• Wheezing may be present
• Pleural friction rub

Heart

• Pericardial friction rub

Abdomen

• Abdominal tenderness in the right/left upper/lower abdominal quadrant
• Rebound tenderness
• Hepatomegaly

Back

• Tenderness over lumbar vertebrae can occur
• Sacral edema may be seen

Genitourinary

• Rashes can be seen

Neuromuscular

• Altered mental status with psychosis
• Peripheral neuropathy

Extremities

• Pitting/non-pitting edema of the lower extremities
• Muscle atrophy
• Fasciculations in the upper/lower extremity