UTY (gene): Difference between revisions
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*{{cite journal |vauthors=Lahn BT, Page DC |title=Functional coherence of the human Y chromosome |journal=Science |volume=278 |issue= 5338 |pages= 675–680 |year= 1997 |pmid= 9381176 |doi=10.1126/science.278.5338.675 }} | *{{cite journal |vauthors=Lahn BT, Page DC |title=Functional coherence of the human Y chromosome |journal=Science |volume=278 |issue= 5338 |pages= 675–680 |year= 1997 |pmid= 9381176 |doi=10.1126/science.278.5338.675 |bibcode=1997Sci...278..675L }} | ||
*{{cite journal | author=Grbavec D |title=Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms |journal=Biochem. J. |volume=337 |issue= 1|pages= 13–7 |year= 1999 |pmid= 9854018 |doi= 10.1042/0264-6021:3370013| pmc=1219929 |name-list-format=vanc| author2=Lo R | author3=Liu Y | display-authors=3 | last4=Greenfield | first4=Andy | last5=Stifani | first5=Stefano }} | *{{cite journal | author=Grbavec D |title=Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms |journal=Biochem. J. |volume=337 |issue= 1|pages= 13–7 |year= 1999 |pmid= 9854018 |doi= 10.1042/0264-6021:3370013| pmc=1219929 |name-list-format=vanc| author2=Lo R | author3=Liu Y | display-authors=3 | last4=Greenfield | first4=Andy | last5=Stifani | first5=Stefano }} | ||
*{{cite journal | author=Warren EH |title=The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen |journal=J. Immunol. |volume=164 |issue= 5 |pages= 2807–14 |year= 2000 |pmid= 10679124 |doi= 10.4049/jimmunol.164.5.2807|name-list-format=vanc| author2=Gavin MA | author3=Simpson E | display-authors=3 | last4=Chandler | first4=P | last5=Page | first5=DC | last6=Disteche | first6=C | last7=Stankey | first7=KA | last8=Greenberg | first8=PD | last9=Riddell | first9=SR }} | *{{cite journal | author=Warren EH |title=The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen |journal=J. Immunol. |volume=164 |issue= 5 |pages= 2807–14 |year= 2000 |pmid= 10679124 |doi= 10.4049/jimmunol.164.5.2807|name-list-format=vanc| author2=Gavin MA | author3=Simpson E | display-authors=3 | last4=Chandler | first4=P | last5=Page | first5=DC | last6=Disteche | first6=C | last7=Stankey | first7=KA | last8=Greenberg | first8=PD | last9=Riddell | first9=SR }} | ||
*{{cite journal |vauthors=Foresta C, Ferlin A, Moro E |title=Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility |journal=Hum. Mol. Genet. |volume=9 |issue= 8 |pages= 1161–1169 |year= 2000 |pmid= 10767340 |doi=10.1093/hmg/9.8.1161 }} | *{{cite journal |vauthors=Foresta C, Ferlin A, Moro E |title=Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility |journal=Hum. Mol. Genet. |volume=9 |issue= 8 |pages= 1161–1169 |year= 2000 |pmid= 10767340 |doi=10.1093/hmg/9.8.1161 }} | ||
*{{cite journal | author=Shen P |title=Population genetic implications from sequence variation in four Y chromosome genes |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 13 |pages= 7354–7359 |year= 2000 |pmid= 10861003 |doi=10.1073/pnas.97.13.7354 | pmc=16549 |name-list-format=vanc| author2=Wang F | author3=Underhill PA | display-authors=3 | last4=Franco | first4=C | last5=Yang | first5=WH | last6=Roxas | first6=A | last7=Sung | first7=R | last8=Lin | first8=AA | last9=Hyman | first9=RW }} | *{{cite journal | author=Shen P |title=Population genetic implications from sequence variation in four Y chromosome genes |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 13 |pages= 7354–7359 |year= 2000 |pmid= 10861003 |doi=10.1073/pnas.97.13.7354 | pmc=16549 |name-list-format=vanc| author2=Wang F | author3=Underhill PA | display-authors=3 | last4=Franco | first4=C | last5=Yang | first5=WH | last6=Roxas | first6=A | last7=Sung | first7=R | last8=Lin | first8=AA | last9=Hyman | first9=RW |bibcode=2000PNAS...97.7354S}} | ||
*{{cite journal | author=Vogt MH |title=UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft rejection: characterization of the critical polymorphic amino acid residues for T-cell recognition |journal=Blood |volume=96 |issue= 9 |pages= 3126–32 |year= 2000 |pmid= 11049993 |doi= |name-list-format=vanc| author2=Goulmy E | author3=Kloosterboer FM | display-authors=3 | last4=Blokland | first4=E | last5=De Paus | first5=RA | last6=Willemze | first6=R | last7=Falkenburg | first7=JH }} | *{{cite journal | author=Vogt MH |title=UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft rejection: characterization of the critical polymorphic amino acid residues for T-cell recognition |journal=Blood |volume=96 |issue= 9 |pages= 3126–32 |year= 2000 |pmid= 11049993 |doi= |name-list-format=vanc| author2=Goulmy E | author3=Kloosterboer FM | display-authors=3 | last4=Blokland | first4=E | last5=De Paus | first5=RA | last6=Willemze | first6=R | last7=Falkenburg | first7=JH }} | ||
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M}} | ||
*{{cite journal | author=Gevaert K |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–569 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 |name-list-format=vanc| author2=Goethals M | author3=Martens L | display-authors=3 | last4=Van Damme | first4=Jozef | last5=Staes | first5=An | last6=Thomas | first6=Grégoire R. | last7=Vandekerckhove | first7=Joël }} | *{{cite journal | author=Gevaert K |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–569 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 |name-list-format=vanc| author2=Goethals M | author3=Martens L | display-authors=3 | last4=Van Damme | first4=Jozef | last5=Staes | first5=An | last6=Thomas | first6=Grégoire R. | last7=Vandekerckhove | first7=Joël }} | ||
*{{cite journal | author=Skaletsky H |title=The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes |journal=Nature |volume=423 |issue= 6942 |pages= 825–837 |year= 2003 |pmid= 12815422 |doi= 10.1038/nature01722 |name-list-format=vanc| author2=Kuroda-Kawaguchi T | author3=Minx PJ | display-authors=3 | last4=Cordum | first4=Holland S. | last5=Hillier | first5=Ladeana | last6=Brown | first6=Laura G. | last7=Repping | first7=Sjoerd | last8=Pyntikova | first8=Tatyana | last9=Ali | first9=Johar }} | *{{cite journal | author=Skaletsky H |title=The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes |journal=Nature |volume=423 |issue= 6942 |pages= 825–837 |year= 2003 |pmid= 12815422 |doi= 10.1038/nature01722 |name-list-format=vanc| author2=Kuroda-Kawaguchi T | author3=Minx PJ | display-authors=3 | last4=Cordum | first4=Holland S. | last5=Hillier | first5=Ladeana | last6=Brown | first6=Laura G. | last7=Repping | first7=Sjoerd | last8=Pyntikova | first8=Tatyana | last9=Ali | first9=Johar |bibcode=2003Natur.423..825S}} | ||
*{{cite journal |vauthors=Agate RJ, Choe M, Arnold AP |title=Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches |journal=Mol. Biol. Evol. |volume=21 |issue= 2 |pages= 384–396 |year= 2004 |pmid= 14660691 |doi= 10.1093/molbev/msh027 }} | *{{cite journal |vauthors=Agate RJ, Choe M, Arnold AP |title=Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches |journal=Mol. Biol. Evol. |volume=21 |issue= 2 |pages= 384–396 |year= 2004 |pmid= 14660691 |doi= 10.1093/molbev/msh027 }} | ||
*{{cite journal |vauthors=Gerrard DT, Filatov DA |title=Positive and negative selection on mammalian Y chromosomes |journal=Mol. Biol. Evol. |volume=22 |issue= 6 |pages= 1423–1432 |year= 2005 |pmid= 15758204 |doi= 10.1093/molbev/msi128 }} | *{{cite journal |vauthors=Gerrard DT, Filatov DA |title=Positive and negative selection on mammalian Y chromosomes |journal=Mol. Biol. Evol. |volume=22 |issue= 6 |pages= 1423–1432 |year= 2005 |pmid= 15758204 |doi= 10.1093/molbev/msi128 }} | ||
Latest revision as of 08:11, 9 January 2019
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| Location (UCSC) | n/a | n/a | |||||
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Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene.[1][2][3]
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative splicing results in multiple transcript variants encoding different isoforms.[3]
Interactions
UTY (gene) has been shown to interact with TLE1,[4] and WDR90[5]
References
- ↑ Greenfield A, Scott D, Pennisi D, Ehrmann I, Ellis P, Cooper L, Simpson E, Koopman P (Jan 1997). "An H-YDb epitope is encoded by a novel mouse Y chromosome gene". Nat Genet. 14 (4): 474–478. doi:10.1038/ng1296-474. PMID 8944031.
- ↑ Greenfield A, Carrel L, Pennisi D, Philippe C, Quaderi N, Siggers P, Steiner K, Tam PP, Monaco AP, Willard HF, Koopman P (May 1998). "The UTX gene escapes X inactivation in mice and humans". Hum Mol Genet. 7 (4): 737–742. doi:10.1093/hmg/7.4.737. PMID 9499428.
- ↑ 3.0 3.1 "Entrez Gene: UTY ubiquitously transcribed tetratricopeptide repeat gene, Y-linked".
- ↑ Grbavec, D; Lo R; Liu Y; Greenfield A; Stifani S (Jan 1999). "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms". Biochem. J. ENGLAND. 337 (1): 13–7. doi:10.1042/0264-6021:3370013. ISSN 0264-6021. PMC 1219929. PMID 9854018.
- ↑ "STRING: functional protein association networks". string-db.org. Retrieved 2015-05-07.
Further reading
- Lahn BT, Page DC (1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–680. Bibcode:1997Sci...278..675L. doi:10.1126/science.278.5338.675. PMID 9381176.
- Grbavec D, Lo R, Liu Y, et al. (1999). "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms". Biochem. J. 337 (1): 13–7. doi:10.1042/0264-6021:3370013. PMC 1219929. PMID 9854018.
- Warren EH, Gavin MA, Simpson E, et al. (2000). "The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen". J. Immunol. 164 (5): 2807–14. doi:10.4049/jimmunol.164.5.2807. PMID 10679124.
- Foresta C, Ferlin A, Moro E (2000). "Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility". Hum. Mol. Genet. 9 (8): 1161–1169. doi:10.1093/hmg/9.8.1161. PMID 10767340.
- Shen P, Wang F, Underhill PA, et al. (2000). "Population genetic implications from sequence variation in four Y chromosome genes". Proc. Natl. Acad. Sci. U.S.A. 97 (13): 7354–7359. Bibcode:2000PNAS...97.7354S. doi:10.1073/pnas.97.13.7354. PMC 16549. PMID 10861003.
- Vogt MH, Goulmy E, Kloosterboer FM, et al. (2000). "UTY gene codes for an HLA-B60-restricted human male-specific minor histocompatibility antigen involved in stem cell graft rejection: characterization of the critical polymorphic amino acid residues for T-cell recognition". Blood. 96 (9): 3126–32. PMID 11049993.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–569. doi:10.1038/nbt810. PMID 12665801.
- Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, et al. (2003). "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes". Nature. 423 (6942): 825–837. Bibcode:2003Natur.423..825S. doi:10.1038/nature01722. PMID 12815422.
- Agate RJ, Choe M, Arnold AP (2004). "Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches". Mol. Biol. Evol. 21 (2): 384–396. doi:10.1093/molbev/msh027. PMID 14660691.
- Gerrard DT, Filatov DA (2005). "Positive and negative selection on mammalian Y chromosomes". Mol. Biol. Evol. 22 (6): 1423–1432. doi:10.1093/molbev/msi128. PMID 15758204.
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