ULBP2

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UL16 binding protein 2
Identifiers
Symbols ULBP2 ; N2DL2; RAET1H
External IDs Template:OMIM5 HomoloGene88904
RNA expression pattern
File:PBB GE ULBP2 221291 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

UL16 binding protein 2, also known as ULBP2, is a human gene.[1]


References

  1. "Entrez Gene: ULBP2 UL16 binding protein 2".

Further reading

  • Cerwenka A, Lanier LL (2004). "NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer". Tissue Antigens. 61 (5): 335–43. PMID 12753652.
  • Cosman D, Müllberg J, Sutherland CL; et al. (2001). "ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor". Immunity. 14 (2): 123–33. PMID 11239445.
  • Onda H, Ohkubo S, Shintani Y; et al. (2001). "A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers". Biochem. Biophys. Res. Commun. 285 (2): 235–43. doi:10.1006/bbrc.2001.5149. PMID 11444831.
  • Steinle A, Li P, Morris DL; et al. (2001). "Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family". Immunogenetics. 53 (4): 279–87. PMID 11491531.
  • Sutherland CL, Chalupny NJ, Schooley K; et al. (2002). "UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells". J. Immunol. 168 (2): 671–9. PMID 11777960.
  • Radosavljevic M, Cuillerier B, Wilson MJ; et al. (2002). "A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3". Genomics. 79 (1): 114–23. doi:10.1006/geno.2001.6673. PMID 11827464.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Dunn C, Chalupny NJ, Sutherland CL; et al. (2003). "Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity". J. Exp. Med. 197 (11): 1427–39. doi:10.1084/jem.20022059. PMID 12782710.
  • Rölle A, Mousavi-Jazi M, Eriksson M; et al. (2003). "Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein". J. Immunol. 171 (2): 902–8. PMID 12847260.
  • Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
  • Eleme K, Taner SB, Onfelt B; et al. (2004). "Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D". J. Exp. Med. 199 (7): 1005–10. doi:10.1084/jem.20032194. PMID 15051759.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Rohner A, Langenkamp U, Siegler U; et al. (2007). "Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis". Leuk. Res. 31 (10): 1393–402. doi:10.1016/j.leukres.2007.02.020. PMID 17391757.

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