Type page name here pathophysiology: Difference between revisions
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==Pathogenesis== | ==Pathogenesis== | ||
The causative viral agents can reach the nervous system via the blood or the nerves themselves. There is difference in both pathways pathogenesis. Viral spreading through the blood (viremia) is more common in viral meningitis pathogenesis. | The causative viral agents can reach the nervous system via the blood or the nerves themselves. There is a difference in both pathways pathogenesis. Viral spreading through the blood (viremia) is more common in viral meningitis pathogenesis. The viruses enter to the pulmonary and intestinal mucosa at which they spread into the blood to reach the lymph nodes where viral replication takes place and this is called primary viremia. At this point, the host cells try to prevent further replication from happening and if they fail to stop the replication, secondary viremia will take place and the viruses can spread to the nervous system. <ref name="pmid11051293">{{cite journal| author=Rotbart HA| title=Viral meningitis. | journal=Semin Neurol | year= 2000 | volume= 20 | issue= 3 | pages= 277-92 | pmid=11051293 | doi=10.1055/s-2000-9427 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11051293 }} </ref> | ||
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==Transmission== | ==Transmission== | ||
Revision as of 15:56, 27 March 2017
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Viral meningitis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Viral meningitis pathophysiology depends on the causative agent. Pathogenesis may differ from virus to another.
Pathogenesis
The causative viral agents can reach the nervous system via the blood or the nerves themselves. There is a difference in both pathways pathogenesis. Viral spreading through the blood (viremia) is more common in viral meningitis pathogenesis. The viruses enter to the pulmonary and intestinal mucosa at which they spread into the blood to reach the lymph nodes where viral replication takes place and this is called primary viremia. At this point, the host cells try to prevent further replication from happening and if they fail to stop the replication, secondary viremia will take place and the viruses can spread to the nervous system. [1]
Transmission
Genetics
Associated conditions
Gross pathology
Microscopic pathology
References
- ↑ Rotbart HA (2000). "Viral meningitis". Semin Neurol. 20 (3): 277–92. doi:10.1055/s-2000-9427. PMID 11051293.