Tumor necrosis factor receptor
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Overview
A tumor necrosis factor receptor (TNFR) is, as its name would indicate, a receptor which binds tumor necrosis factors (TNF).
Because "TNF" is often used to describe TNF alpha, "TNFR" is often used to describe the receptors that bind to TNF alpha - namely, CD120. However, there several other members of this family that bind to the other TNFs.[1][2]
Members
Family members include:[1]
- type 1
- type 3
- type 4
- type 5
- type 6
- type 7
- type 8
- type 9
- type 10
- type 11
- type 12
- type 13
- type 14
- type 16
- type 17
- type 18
- type 19
- type 21
- type 25
References
- ↑ 1.0 1.1 Locksley RM, Killeen N, Lenardo MJ (2001). "The TNF and TNF receptor superfamilies: integrating mammalian biology". Cell. 104 (4): 487–501. doi:10.1016/S0092-8674(01)00237-9. PMID 11239407.
- ↑ Hehlgans T, Pfeffer K (2005). "The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games". Immunology. 115 (1): 1–20. doi:10.1111/j.1365-2567.2005.02143.x. PMID 15819693.
External links
- Tumor+Necrosis+Factor+Receptor at the US National Library of Medicine Medical Subject Headings (MeSH)