Tumor lysis syndrome risk factors: Difference between revisions

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{{Tumor lysis syndrome}}
{{Tumor lysis syndrome}}
{{CMG}} {{AE}} {{MJK}}
{{CMG}} {{AE}} {{MJK}}  {{N.F}}
==Overview==
==Overview==
The most potent risk factor in the development of tumor lysis syndrome after initiating [[chemotherapy]] is [[kidney disease]]. Other risk factors include [[dehydration]], hematologic tumors, and solid tumors.
The most potent risk factor in the development of tumor lysis syndrome after initiating [[chemotherapy]] is [[kidney disease]]. Other risk factors include [[dehydration]], hematologic tumors, and solid tumors.


==Risk Factors==
==Risk Factors==
The followings are risk factors for developing tumor lysis syndrome after initiating chemotherapy:
The followings are risk factors for developing tumor lysis syndrome after initiating chemotherapy:<ref name="urlwww.asn-online.org">{{cite web |url=https://www.asn-online.org/education/distancelearning/curricula/onco/Chapter4.pdf |title=www.asn-online.org |format= |work= |accessdate=}}</ref>
*Hematologic malignancies:
:*Acute leukemia (highest rate with [[acute lymphoblastic leukemia]])
:*[[Non-Hodgkin lymphoma]]
:*[[Multiple myeloma]]


*Other malignancies:
=== Common Risk Factors ===
:*[[Breast cancer]]
* Common risk factors in the development of tumor lysis syndrome include:<ref name="pmid25938028">{{cite journal |vauthors=Mirrakhimov AE, Voore P, Khan M, Ali AM |title=Tumor lysis syndrome: A clinical review |journal=World J Crit Care Med |volume=4 |issue=2 |pages=130–8 |date=May 2015 |pmid=25938028 |pmc=4411564 |doi=10.5492/wjccm.v4.i2.130 |url=}}</ref>
:*[[Ovarian cancer]]
** [[acute lymphoblastic leukemia]]
:*[[Hepatocellular carcinoma]]
** [[Non-Hodgkin lymphoma]]
:*[[Lung cancer]]
** [[Burkitt's lymphoma|Burkitts lymphoma]]
:*[[Sarcomas]]
** Older age
:*[[Germ cell tumor]]
** [[Dehydration]]
:*[[Melanoma]]
** [[Non-steroidal anti-inflammatory drug|Non-steroidal anti-inflammatory drugs]]
** [[ACE inhibitor|Angiotensin converting enzyme inhibitors]]
** [[angiotensin receptor blockers]]
 
=== Less Common Risk Factors ===
* Less common risk factors in the development of TLS include:<ref name="pmid25938028" />
** [[Multiple myeloma]]
** [[Melanoma]]
** [[Breast cancer]]
**[[Ovarian cancer]]
**[[Hepatocellular carcinoma]]
**[[Lung cancer]]
**[[Sarcomas]]


==References==
==References==
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[[Category:Blood]]
[[Category:Blood]]
[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]

Latest revision as of 19:33, 27 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Nazia Fuad M.D.

Overview

The most potent risk factor in the development of tumor lysis syndrome after initiating chemotherapy is kidney disease. Other risk factors include dehydration, hematologic tumors, and solid tumors.

Risk Factors

The followings are risk factors for developing tumor lysis syndrome after initiating chemotherapy:[1]

Common Risk Factors

Less Common Risk Factors

References

  1. "www.asn-online.org" (PDF).
  2. 2.0 2.1 Mirrakhimov AE, Voore P, Khan M, Ali AM (May 2015). "Tumor lysis syndrome: A clinical review". World J Crit Care Med. 4 (2): 130–8. doi:10.5492/wjccm.v4.i2.130. PMC 4411564. PMID 25938028.

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