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==Overview==
==Overview==
Tuberculosis may be classified according to its pathogenesis into 6 categories.  This classification divides patients from class 0, in which the person hasn't been exposed to TB, and has a negative TST and IGRA, to class 5, in which the patient
Tuberculosis may be classified according to its pathogenesis into 6 categories.  This classification divides patients from class 0, in which the person hasn't been exposed to TB, and has a negative TST and IGRA, to class 5, in which the [[TB]] is suspected, there are [[signs]] and [[symptoms]] of the disease, but the evaluation is not complete to confirm the diagnosis.
==Classification==
==Classification==
Below is a table with the current classification system of [[tuberculosis]] ([[TB]]), based on its [[pathogenesis]]:<ref name=CDC>{{cite web | title = TB Classification | url = http://www.cdc.gov/tb/publications/slidesets/selfstudymodules/module1/classification.htm }}</ref>  
Below is a table with the current classification system of [[tuberculosis]] ([[TB]]), based on its [[pathogenesis]]:<ref name=CDC>{{cite web | title = TB Classification | url = http://www.cdc.gov/tb/publications/slidesets/selfstudymodules/module1/classification.htm }}</ref>  

Revision as of 22:15, 5 September 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Tuberculosis may be classified according to its pathogenesis into 6 categories. This classification divides patients from class 0, in which the person hasn't been exposed to TB, and has a negative TST and IGRA, to class 5, in which the TB is suspected, there are signs and symptoms of the disease, but the evaluation is not complete to confirm the diagnosis.

Classification

Below is a table with the current classification system of tuberculosis (TB), based on its pathogenesis:[1]

Class Type of Tuberculosis Description

0

No TB exposure
Not infected

No history of TB exposure
Negative result to a TST or IGRA

1

TB exposure
No evidence of infection

History of TB exposure
Negative result to a TST (given at least 8-10 weeks after exposure) or IGRA

2

TB infection
No TB disease

Positive result to a TST or IGRA
Negative smears and cultures (if done)
No clinical or x-ray evidence of active TB disease

3

Clinically active TB

Positive culture (if done) for M. tuberculosis
Positive result to a TST or IGRA, and clinical, bacteriological, or x-ray evidence of TB disease

4

Previous TB disease (not clinically active)

Medical history of TB disease
Abnormal but stable x-ray findings
Positive result to a TST or IGRA
Negative smears and cultures (if done)
No clinical or x-ray evidence of active TB disease

5

Suspected TB

Signs and symptoms of TB disease, but evaluation not complete

CDC TB Classification for Immigrants and Refugees

Tuberculosis classification for immigrants and refugees according to the U.S. Citizenship and Immigration Services, developed by the Centers for Disease Control and Prevention (CDC):[2]

Class Description

No TB Classification

Applicants with normal tuberculosis screening examinations

Class A TB with waiver

All applicants who have tuberculosis disease and have been granted a waiver

Class B1 TB, Pulmonary

No treatment:

  • Have negative acid-fast bacilli sputum smears
  • Have negative cultures
  • Are not diagnosed with tuberculosis
  • Can wait to have tuberculosis treatment started after immigration

Completed treatment:

  • Applicants who were diagnosed with pulmonary tuberculosis and successfully completed directly observed therapy prior to immigration
  • The cover sheet should indicate if the initial sputum smears and cultures were positive and if drug susceptibility testing results are available

Class B1 TB, Extrapulmonary

Applicants with evidence of extrapulmonary tuberculosis
The anatomic site of infection should be documented

Class B2 TB, LTBI Evaluation

Applicants who have a tuberculin skin test ≥10 mm or positive IGRA but otherwise have a negative evaluation for tuberculosis
The size of the TST reaction or IGRA result, the applicant’s status with respect to latent TB infection (LTBI) treatment, and the medication(s) used should be documented
For applicants who had more than one TST or IGRA, all dates and results and whether the applicant’s TST or IGRA converted should be documented
Contacts with TST ≥5 mm or positive IGRA should receive this classification (if they are not already Class B1 TB, Pulmonary)

Class B3 TB, Contact Evaluation

Applicants who are a recent contact of a known tuberculosis case
The size of the applicant’s TST reaction or IGRA response should be documented
Information about the source case, name, alien number, relationship to contact, and type of tuberculosis should also be documented.

References

  1. "TB Classification".
  2. "TB Classification US Citizenship and Immigration Services" (PDF).

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