Tropical sprue laboratory findings
|
Tropical sprue Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Tropical sprue laboratory findings On the Web |
|
American Roentgen Ray Society Images of Tropical sprue laboratory findings |
|
Risk calculators and risk factors for Tropical sprue laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
All the patients with celiac disease unresponsive to gluten free diet, a diagnosis of tropical sprue must be considered. The lab findings are not specific for tropical sprue as it is a diagnosis of exlclusion. [1]
- Patients with ileal involvement have low vitamin B12 and folate levels
- Normal transglutaminase, immunoglobulin levels are present.
Approach to a Patient With Malabsorption in Tropical Region
| Clinical suspicion of malabsoption syndrome | |||||||||||||||||||||||||||||||||||||||||||||||
| Initial screening perform: Hemogram Stool Microscopy D-xylose test Fecal fat | |||||||||||||||||||||||||||||||||||||||||||||||
| Confirmatory tests for malabsoption should be done | |||||||||||||||||||||||||||||||||||||||||||||||
| Antiendomysial antibodies and villous atrophy suggests celiac disease Breath test for lactase deficiency Microscopy and culture of jejunal aspirate for small bowel bacterial overgrowth Serum immunoglobulin for B-celll deficiency HIV serology CT enterography | |||||||||||||||||||||||||||||||||||||||||||||||
| Once all other possibilities are ruled out, suspect diagnosis of tropical sprue | |||||||||||||||||||||||||||||||||||||||||||||||
| Start tetracycline therapy Improvement of symptoms with tetracycline confirms the diagnosis | |||||||||||||||||||||||||||||||||||||||||||||||
References
- ↑ Bonnefoy S, Chauvin A, Galéano-Cassaz C, Camilleri-Broet S, Jacquet SF, Carmoi T; et al. (2012). "[Tropical sprue in an expatriate]". Rev Med Interne. 33 (5): 284–7. doi:10.1016/j.revmed.2012.01.015. PMID 22405324.