Tropical sprue laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
Routine tests for TS: | |||
* Hemoglobin | |||
* Mean corpuscular volume | |||
* LDH | |||
* Folic acid | |||
* Vitamin B12 | |||
Serological findings: | |||
* Anti-gliadin antibodies | |||
* Anti-endomysial antibodies | |||
* Anti-tissue transgltaminase antibodies | |||
* Testing for other antibodies. | |||
Tropical Sprue can be diagnosed using the following tests and exams: | Tropical Sprue can be diagnosed using the following tests and exams: | ||
===Stool Examination=== | ===Stool Examination=== | ||
* The stools are usually increased in volume and are either watery, or semiformed. | * The stools are usually increased in volume and are either watery, or semiformed. | ||
Revision as of 20:29, 22 February 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
Routine tests for TS:
- Hemoglobin
- Mean corpuscular volume
- LDH
- Folic acid
- Vitamin B12
Serological findings:
- Anti-gliadin antibodies
- Anti-endomysial antibodies
- Anti-tissue transgltaminase antibodies
- Testing for other antibodies.
Tropical Sprue can be diagnosed using the following tests and exams:
Stool Examination
- The stools are usually increased in volume and are either watery, or semiformed.
- The finding of fat globules in stool is very suggestive of the presence of steatorrhea.
- It is also helpful to exclude some of the parasites causing chronic diarrhea such as Giardia Lamblia, Entamoeba Histolytic.
Sigmoidoscopy
- Performed in all patients with chronic diarrhea to exclude lesions other than sprue such as amebiasis.
- In sprue, there is hyperemia of the colonic mucosa without ulcerations.
Gastric biopsy
- Shows achlorhydria and changes ranging from superficial gastritis through chronic gastritis to complete gastric atrophy.
Absorption studies
- Steatorrhea may be essential for the diagnosis of TS.
- Bone density test
- CHEM 20
- Complete blood count (CBC)
- Comprehensive metabolic panel
- Enteroscopy
- Folate level (serum)
- Iron level (serum)
- Stool examination for bacteria and parasites
- Upper endoscopy
- Upper GI series
- Vitamin B12 level (serum)
- Vitamin D level