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'''Differentiating Tropical sprue from other causes of Tropical malabsorption'''
'''Differentiating Tropical sprue from other causes of Tropical malabsorption'''
! colspan="2" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Causes}}
! colspan="2" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Causes}}
!Endemic area
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Pathophysiology and Histology}}
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Pathophysiology and Histology}}
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Acute diarrhea}}
!colspan="1" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Acute diarrhea}}
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! colspan="2" |Tropical sprue
! colspan="2" |Tropical sprue
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! colspan="2" |Tropical Enteropathy
!Increased mucosal permeability, shorter villi, elongated crypts and increased lymphocytes in the lamina propria
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!Subclinical
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! rowspan="4" | '''Infectious'''
! rowspan="4" | '''Infectious'''
!Protozoal
!Protozoal
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*  
*  
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!Helminths
!Helminths
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!Bacterial
!Bacterial
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!Viral
!Viral
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! rowspan="3" |Inflammatory and Immune mediated
! rowspan="3" |Inflammatory and Immune mediated
!Crohn's disease
!Crohn's disease
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!Decreased small intestinal absorptive surface area
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!Ulcerative colitis
!Ulcerative colitis
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!Coeliac sprue
!Coeliac sprue
!Uncommon in the tropics, usually seen in the Northern India and Saharawi  in Africa
!Complete villous atrophy of the jejunal mucosa
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|Antiendomysial and tissue transglutaminase  antibodies
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|Clinical and histological response to gluten withdrawal.
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!Malignant
!Malignant
!Intestinal Lymphoma
!Intestinal Lymphoma
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! colspan="2" |Pancreatic disease
! colspan="2" |Pancreatic disease
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! colspan="2" |Irritable bowel syndrome
! colspan="2" |Irritable bowel syndrome
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Revision as of 16:29, 21 February 2017

Tropical sprue Microchapters

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Overview

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Differentiating Tropical sprue from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tropical sprue must be differentiated from celiac disease, chronic diarrhea, Clonorchiasis, traveler's diarrhea, and whipworm.

Differentiating Tropical sprue from other Diseases

Differentiating Tropical sprue from other causes of Tropical malabsorption
Causes Pathophysiology and Histology Acute diarrhea Traveller's diarrhea Chronic diarrhea Malabsorption Steatorrhoea Diagnosis Confirmatory tests Associations
Tropical sprue
Tropical Enteropathy Increased mucosal permeability, shorter villi, elongated crypts and increased lymphocytes in the lamina propria Subclinical
Infectious Protozoal
Helminths
Bacterial
Viral
Inflammatory and Immune mediated Crohn's disease Decreased small intestinal absorptive surface area
Ulcerative colitis
Coeliac sprue Complete villous atrophy of the jejunal mucosa Antiendomysial and tissue transglutaminase antibodies Clinical and histological response to gluten withdrawal.
Malignant Intestinal Lymphoma
Pancreatic disease
Irritable bowel syndrome

Chronic diarrhea

  • Tropical sprue
  • Ulcerative Colitis,
  • Crohn's disease
  • Diarrhea, chronic responsive to antiparasitic drugs
  • Diarrhea, chronic unknown
  • Inflammatory bowel disease, new onset post-travel (Crohn or ulcerative colitis)
  • Irritable bowel syndrome
  • Irritable bowel syndrome, post infectious
  • Lactose intolerance, post infectious
  • Malabsorption

Acute diarrhea

  • E. coli
  • Clostridium difficile-associated disease
  • Campylobacter
  • Cholera (toxigenic Vibrio cholerae)
  • Cryptosporidium
  • Cyclospora
  • Diarrhea, acute bacterial
  • Diarrhea, acute parasitic
  • Diarrhea, acute unspecified
  • Diarrhea, acute viral
  • Dysentery, acute unspecified
  • Entamoeba histolytica, ameba
  • E. histolytica, diarrhea
  • E. histolytica, dysentery
  • Food poisoning
  • Gastroenteritis
  • Giardia
  • Isospora
  • Noncholera Vibrio
  • Salmonella, other
  • Shiga toxin-producing Escherichia coli
  • Shigella, S. boydii
  • Shigella, S. dysenteriae
  • Shigella, S. flexneri

The following diseases have a similar presentation to tropical sprue.

References

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