Tropane alkaloid
Tropane alkaloids, also known as Belladonna alkaloids are a class of alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae.
Important tropane alkaloids are:
Anticholinergics
Anticholinergic drugs and deliriants:
- Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna)
- Hyoscyamine, the levo-isomer of atropine, from henbane (Hyoscamus niger) and mandrake (Mandragora officinalis)
- Scopolamine, from henbane and Datura species (Jimson weed)
Stimulants
Stimulants and cocaine-related alkaloids:
- Cocaine, from Erythroxylum coca
- Ecgonidine, and methylecgonidine, pyrolysis products of cocaine
- Ecgonine, a precursor and metabolite of cocaine
- Benzoylecgonine, a metabolite of cocaine
- Cocaethylene, a metabolite of cocaine
- Hydroxytropacocaine, from Erythroxylum coca
- Methylecgonine cinnamate, from Erythroxylum coca
Others
- Catuabines, found in the drug catuaba, from Erythroxylum vacciniifolium
Non-natural tropanes