Trilostane

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Trilostane
File:Trilostane.svg
Clinical data
ATC code
Legal status
Legal status
  • Withdrawn (U.S.)
Pharmacokinetic data
Elimination half-life8 hours
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC20H27NO3
Molar mass329.433 g/mol

Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.[1] It was withdrawn from the United States market in April 1994.

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References

  1. Komanicky P, Spark RF, Melby JC. (1978). "Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis". Journal of Clinical Endocrinology and Metabolism. 47 (5): 1042–1051. PMID 233687. |access-date= requires |url= (help)

Template:Corticosteroids for systemic use