Transposition of the great vessels natural History, complications & prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
* Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year. | * Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year.<ref name="pmid12324738">{{cite journal |vauthors=Hutter PA, Kreb DL, Mantel SF, Hitchcock JF, Meijboom EJ, Bennink GB |title=Twenty-five years' experience with the arterial switch operation |journal=J. Thorac. Cardiovasc. Surg. |volume=124 |issue=4 |pages=790–7 |date=October 2002 |pmid=12324738 |doi=10.1067/mtc.2002.120714 |url=}}</ref> | ||
*The prognosis for patients with D-TGA is generally excellent following surgical correction. | *The prognosis for patients with D-TGA is generally excellent following surgical correction. | ||
*Current survival rates are greater than 90%. | *Current survival rates are greater than 90%. | ||
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**Presence of one or more of the above mentioned defects are present, blood will be mixed, allowing a small amount of oxygen to be delivered to the body, giving an opportunity to the newborn to survive long enough to receive corrective surgery. | **Presence of one or more of the above mentioned defects are present, blood will be mixed, allowing a small amount of oxygen to be delivered to the body, giving an opportunity to the newborn to survive long enough to receive corrective surgery. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 17:44, 21 February 2020
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Transposition of the great vessels Microchapters |
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Classification |
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Differentiating Transposition of the great vessels from other Diseases |
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Diagnosis |
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Treatment |
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Surgery |
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Case Studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]
Overview
Natural History
Complications
Common complications of TGA include:[1]
- Congestive heart failure
- Arrhythmia
- Eisenmenger syndrome (irreversible and progressive pulmonary vascular obstructive disease)
- Pulmonary artery stenosis
- Coronary artery ostial obstruction (coronary ischemia)
- Rarely can lead to supravalvular aortic stenosis
- Aortic root dilation
- Aortic regurgitation
Prognosis
- Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year.[2]
- The prognosis for patients with D-TGA is generally excellent following surgical correction.
- Current survival rates are greater than 90%.
- The ASO has the best long-term survival and functional outcome.
- Studies have reported a >95% rate survival at fifteen to twenty-five years following discharge.
- The prognosis on simple d-TGA depends mainly on the presence of cardiac shunts such as FO, ASD, VSD, and DA.
- Presence of one or more of the above mentioned defects are present, blood will be mixed, allowing a small amount of oxygen to be delivered to the body, giving an opportunity to the newborn to survive long enough to receive corrective surgery.
References
- ↑ Gatzoulis MA, Walters J, McLaughlin PR, Merchant N, Webb GD, Liu P (October 2000). "Late arrhythmia in adults with the mustard procedure for transposition of great arteries: a surrogate marker for right ventricular dysfunction?". Heart. 84 (4): 409–15. doi:10.1136/heart.84.4.409. PMC 1729461. PMID 10995411.
- ↑ Hutter PA, Kreb DL, Mantel SF, Hitchcock JF, Meijboom EJ, Bennink GB (October 2002). "Twenty-five years' experience with the arterial switch operation". J. Thorac. Cardiovasc. Surg. 124 (4): 790–7. doi:10.1067/mtc.2002.120714. PMID 12324738.