Transitional cell carcinoma laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
* [[Urinalysis]]<ref name="NIH">Bladder Cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/bladder/diagnosis/?region=ab#urinetest Accessed on October, 6 2015 </ref> | * [[Urinalysis]]<ref name="NIH">Bladder Cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/bladder/diagnosis/?region=ab#urinetest Accessed on October, 6 2015 </ref> | ||
:* Blood in the urine | :* Blood in the urine ( Gross/Microscopic) | ||
* Urine cytology | * Urine cytology | ||
:* Abnormal cells in the urine | :* Abnormal cells in the urine | ||
Revision as of 15:31, 9 July 2019
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Transitional cell carcinoma Microchapters |
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Differentiating Transitional cell carcinoma from other Diseases |
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Transitional cell carcinoma laboratory findings On the Web |
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Risk calculators and risk factors for Transitional cell carcinoma laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2] Anum Gull M.B.B.S.[3]
Overview
Laboratory findings consistent with the diagnosis of transitional cell carcinoma include blood in the urine, abnormal cells in the urine, and elevated tumor markers.
Laboratory Findings
- Blood in the urine ( Gross/Microscopic)
- Urine cytology
- Abnormal cells in the urine
- Tumor marker tests: Urine biomarkers could have a significant role in determining which individuals require cystoscopy, as well as determining those who might need evaluation of the upper urinary tract.
- Bladder tumor–associated antigen (BTA)[2]
- Nuclear matrix proteins 22 (NMP)
- NMP52
- Mucin and carcinoembryonic antigen (CEA)
- Hyaluronic acid
- Bladder cancer associated NMP 4 (BLCA-4)
- Survivin
- Cytokeratin (CK) 8 and CK 18
- Low red blood cell count
- Elevated alkaline phosphatase
- UroVysion test is a multicolor FISH assay using probes that can detect aneuploidy of chromosomes 3, 7, or 17 or loss of the 9p21 locus
References
- ↑ Bladder Cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/bladder/diagnosis/?region=ab#urinetest Accessed on October, 6 2015
- ↑ Guo A, Wang X, Gao L, Shi J, Sun C, Wan Z (2014). "Bladder tumour antigen (BTA stat) test compared to the urine cytology in the diagnosis of bladder cancer: A meta-analysis". Can Urol Assoc J. 8 (5–6): E347–52. doi:10.5489/cuaj.1668. PMC 4039599. PMID 24940462.