Toxic multinodular goiter classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Toxic multinodular goiter is classified into three types- Primary, secondary, teritiary hyperthyroidism.

Classification

Based on the origin of the abnormality

Based on the origin of the abnormality the lesions may be classified into primary, secondary, and tertiary hyperthyroidism.[1]

 
 
 
 
 
 
 
 
According to the origin of the abnormality
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Primary hyperthyroidism
 
 
 
 
Secondary hyperthyroidism
 
 
 
 
Tertiary hyperthyroidism
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Grave’s disease
Toxic thyroid nodule
Thyroid adenoma
Multinodular goiter
 
 
 
 
Pituitary adenoma
Intracranial tumors pressing pituitary gland
 
 
 
 
Intracranial tumors or masses involving hypothalamus
 


Based on the iodine uptake

Based on the results of iodine uptake, thyroid disorders may be classified into high uptake, high or normal uptake, and low uptake.[2]

 
 
 
 
 
 
 
 
According to iodine uptake
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
High uptake
 
 
 
 
High or normal uptake
 
 
 
 
Low uptake
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Toxic multinodular goiter
Graves' disease
Toxic thyroid adenoma
 
 
 
 
• Iodine caused hyperthyroidism
Hashitoxicosis
Germ cell tumors (choriocarcinoma in males and testicular germ cell tumors)
Pituitary TSH producing adenoma
 
 
 
 
Subacute thyroiditis
• Hyperthyroidism due to ectopic thyroid tissue
• Factitious thyrotoxicosis
Struma ovarii
• Painless thyroiditis
• Amiodarone induced thyroiditis-Type 1
• Amiodarone induced thyroiditis-Type 2
 

References

  1. Monaco F (2003). "Classification of thyroid diseases: suggestions for a revision". J. Clin. Endocrinol. Metab. 88 (4): 1428–32. doi:10.1210/jc.2002-021260. PMID 12679417.
  2. [+http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)72981-0/abstract "Thyroid disease classification - The Lancet"] Check |url= value (help).

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