Thoracic aortic aneurysm overview: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 11: Line 11:
Two of the most common causes of thoracic aorta aneurysm are [[Marfan's syndrome]] and [[atherosclerosis]].  In some centers, a prior history of dissection with aneurysmal dilation is the most common cause of surgical repair.
Two of the most common causes of thoracic aorta aneurysm are [[Marfan's syndrome]] and [[atherosclerosis]].  In some centers, a prior history of dissection with aneurysmal dilation is the most common cause of surgical repair.


==Common Causes==
==Causes==
#[[Marfan's Syndrome]]
#[[Marfan's Syndrome]]
#[[Atherosclerosis]]
#[[Atherosclerosis]]
#Previous injury to the aorta such as an [[aortic dissection]] is the most common cause of aortic aneurysm repair in some institutions
#Previous injury to the aorta such as an [[aortic dissection]] is the most common cause of aortic aneurysm repair in some institutions
==Causes Based Upon Inherited versus Sporadic versus Syndromic Basis==


==Differentiation of Thoracic Aortic Aneurysm from Other Disorders==
==Differentiation of Thoracic Aortic Aneurysm from Other Disorders==

Revision as of 22:55, 21 October 2012

Thoracic aortic aneurysm Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Thoracic Aortic Aneurysm from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

General Approach to Imaging in Thoracic Aortic Aneurysm

Chest X Ray

MRI

CT

Echocardiography

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Endovascular Stent Grafting

Lifestyle Changes

Special Scenarios

Management during Pregnancy

Case Studies

Case #1

Thoracic aortic aneurysm overview On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Thoracic aortic aneurysm overview

CDC on Thoracic aortic aneurysm overview

Thoracic aortic aneurysm overview in the news

Blogs on Thoracic aortic aneurysm overview

Directions to Hospitals Treating Thoracic aortic aneurysm overview

Risk calculators and risk factors for Thoracic aortic aneurysm overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Editor-in-Chief: Amjad AlMahameed, MD, MPH, RPVI, FACP. Beth Israel Deaconess Medical Center and Harvard Medical School. Boston, USA

Overview

A Thoracic aortic aneurysms (TAA) is defined as an expansion or dilation of the aorta greater than 4.5 cm. Thoracic aortic aneurysms (TAAs) encompass all aneurysms the aorta between the aortic root and the crura of the diaphragm. The aortic root and the ascending thoracic aorta are the most common sites of TAAs (60%), followed by the descending thoracic aorta (40%). Involvement of the aortic arch and/or extension of a TAA into the abdominal aorta (AA) (so called thoracoabdominal aneurysms) are relatively uncommon subsets (each encountered in 10% of cases or less).

Overview

Two of the most common causes of thoracic aorta aneurysm are Marfan's syndrome and atherosclerosis. In some centers, a prior history of dissection with aneurysmal dilation is the most common cause of surgical repair.

Causes

  1. Marfan's Syndrome
  2. Atherosclerosis
  3. Previous injury to the aorta such as an aortic dissection is the most common cause of aortic aneurysm repair in some institutions

Differentiation of Thoracic Aortic Aneurysm from Other Disorders

Thoracic aortic aneurysms are often asymptomatic and as a result can be easily missed. If chest pain is present, it is critical to differentiate a thoracic aortic aneurysm with dissection from other potential life-threatening diseases which include the following:

Risk factors

Hypertension and cigarette smoking are the most important risk factors, though the importance of genetic factors in the development of thoracic aortic aneurysm (such as familial thoracic aortic aneurysm; familial aortic dissection) has been increasingly recognized. Approximately 10% of patients may have other family members who have aortic aneurysms. It is also important to note that individuals with a history of aneurysms in other parts of the body have a higher chance of developing a thoracic aortic aneurysm.[3]

Specific thoracic aortic aneurysm risk factors include:

  • Aortic aneurysms are three time more prevalent in males versus females
  • Race
  • Aortic aneurysms are more frequent in Caucasian individuals versus other races

References

  1. Larsson E, Vishnevskaya L, Kalin B, Granath F, Swedenborg J, Hultgren R (2011). "High frequency of thoracic aneurysms in patients with abdominal aortic aneurysms". Annals of Surgery. 253 (1): 180–4. doi:10.1097/SLA.0b013e3181d96498. PMID 20571364. Unknown parameter |month= ignored (help)
  2. Schubert H (2003). "Thoracic aortic dissection: distinguishing it from acute myocardial infarction". Canadian Family Physician Médecin De Famille Canadien. 49: 583–5. PMC 2214223. PMID 12790268. Unknown parameter |month= ignored (help)
  3. Thoracic Aortic Disease - Northwestern Memorial Hospital. Thoracic Aortic Aneurysm

Template:WH Template:WS