Teratoma pathophysiology: Difference between revisions
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{{CMG}}; {{AE}} {{G.D.}} | {{CMG}}; {{AE}} {{G.D.}} | ||
==Overview== | ==Overview== | ||
The | The histopathology of teratoma depends on the histological subtype.Teratoma is a germ cell tumor due to abnormal development of pluripotent cells. | ||
==Pathophysiology== | ==Pathophysiology== | ||
===Pathogenesis=== | ===Pathogenesis=== | ||
*Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment. | |||
*Mature teratoma comes from a single germ cell tumor after first phase of meiosis.<ref name="LinderMcCaw1975">{{cite journal|last1=Linder|first1=David|last2=McCaw|first2=Barbara Kaiser|last3=Hecht|first3=Frederick|title=Parthenogenic Origin of Benign Ovarian Teratomas|journal=New England Journal of Medicine|volume=292|issue=2|year=1975|pages=63–66|issn=0028-4793|doi=10.1056/NEJM197501092920202}}</ref> | |||
*Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm). | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2]
Overview
The histopathology of teratoma depends on the histological subtype.Teratoma is a germ cell tumor due to abnormal development of pluripotent cells.
Pathophysiology
Pathogenesis
- Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.
- Mature teratoma comes from a single germ cell tumor after first phase of meiosis.[1]
- Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).
References
- ↑ Linder, David; McCaw, Barbara Kaiser; Hecht, Frederick (1975). "Parthenogenic Origin of Benign Ovarian Teratomas". New England Journal of Medicine. 292 (2): 63–66. doi:10.1056/NEJM197501092920202. ISSN 0028-4793.