Teratoma pathophysiology: Difference between revisions

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==Overview==
==Overview==
The exact pathogenesis of teratoma may be understood by the pathology migration of primodial germ cells from the yolk sac to primitive gonads.
The histopathology of teratoma depends on the histological subtype.Teratoma is a germ cell tumor due to abnormal development of pluripotent cells.


==Pathophysiology==
==Pathophysiology==
===Physiology===
===Pathogenesis===
===Pathogenesis===
*Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.
*Mature teratoma comes from a single germ cell tumor after first phase of meiosis.<ref name="LinderMcCaw1975">{{cite journal|last1=Linder|first1=David|last2=McCaw|first2=Barbara Kaiser|last3=Hecht|first3=Frederick|title=Parthenogenic Origin of Benign Ovarian Teratomas|journal=New England Journal of Medicine|volume=292|issue=2|year=1975|pages=63–66|issn=0028-4793|doi=10.1056/NEJM197501092920202}}</ref>
*Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).





Revision as of 19:40, 28 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2]

Overview

The histopathology of teratoma depends on the histological subtype.Teratoma is a germ cell tumor due to abnormal development of pluripotent cells.

Pathophysiology

Pathogenesis

  • Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.
  • Mature teratoma comes from a single germ cell tumor after first phase of meiosis.[1]
  • Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).



References

  1. Linder, David; McCaw, Barbara Kaiser; Hecht, Frederick (1975). "Parthenogenic Origin of Benign Ovarian Teratomas". New England Journal of Medicine. 292 (2): 63–66. doi:10.1056/NEJM197501092920202. ISSN 0028-4793.

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