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{{Teratoma}}
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==Overview==
==Overview==
Teratomas are subtypes of germ cell tumors.Teratomas may be classified into four subgroups based on the histology and site features.
==Classification==
==Classification==
 
*Teratomas may be classified into four subgroups based on the histology features.<ref name="pmid27528018">{{cite journal| author=Zuquello RÁ, Tagliari G, Bagatini R, Camiña RH, Caron R, Lorencette NA et al.| title=Immature teratoma presenting as a soft-tissue mass with no evidence of other sites of involvement: a case report. | journal=Diagn Pathol | year= 2016 | volume= 11 | issue= 1 | pages= 76 | pmid=27528018 | doi=10.1186/s13000-016-0527-x | pmc=4986345 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27528018 }} </ref><ref name="PetersonBuckley2012">{{cite journal|last1=Peterson|first1=Christine M.|last2=Buckley|first2=Celine|last3=Holley|first3=Susan|last4=Menias|first4=Christine O.|title=Teratomas: A Multimodality Review|journal=Current Problems in Diagnostic Radiology|volume=41|issue=6|year=2012|pages=210–219|issn=03630188|doi=10.1067/j.cpradiol.2012.02.001}}</ref><ref name="pmid26894303">{{cite journal| author=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P et al.| title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications. | journal=Arch Gynecol Obstet | year= 2016 | volume= 293 | issue= 4 | pages= 695-700 | pmid=26894303 | doi=10.1007/s00404-016-4035-8 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26894303  }} </ref>
: Teratomas are classifiable based on different general characteristics and site of origin.
**Mature teratoma which is benign cystic and solid.
: Historically teratomas were classified as :
**Immature teratoma which is malignant with some embryonic component.
:* mature
**Malignant teratoma with some somatic malignant neoplasm component.
:* immature
**Monodermal teratoma.
In adults teratomas likely demonstrate malignant inclination and behavior. In Children, different tumors from various origins are reported, while predominantly we may see sacrococcygeal tumors. We can also classify teratomas to benign and malignant tumors. The malignant types are named teratocarcinomasBased on site of origin, teratomas are generally arise from ovary, testicle, or tailbone and less commonly from other areas.<ref name="urlTeratomas: A Multimodality Review - ScienceDirect">{{cite web |url=https://www.sciencedirect.com/science/article/abs/pii/S0363018812000151?via%3Dihub |title=Teratomas: A Multimodality Review - ScienceDirect |format= |work= |accessdate=}}</ref>
*Teratomas may also be classified based on the site:<ref name="pmid29798962">{{cite journal| author=Varma AV, Malpani G, Agrawal P, Malukani K, Dosi S| title=Clinicopathological spectrum of teratomas: An 8-year retrospective study from a tertiary care institute. | journal=Indian J Cancer | year= 2017 | volume= 54 | issue= 3 | pages= 576-579 | pmid=29798962 | doi=10.4103/ijc.IJC_294_17 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29798962  }} </ref>
 
**Intragonadal (ovary and testis).
**Extragonadal (sacrococcygeal, retroperitoneum, mediastinum, and others).
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 19:21, 4 November 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Masoud Bitarafan, M.D[[3]]Amandeep Singh M.D.[4]

Overview

Teratomas are subtypes of germ cell tumors.Teratomas may be classified into four subgroups based on the histology and site features.

Classification

  • Teratomas may be classified into four subgroups based on the histology features.[1][2][3]
    • Mature teratoma which is benign cystic and solid.
    • Immature teratoma which is malignant with some embryonic component.
    • Malignant teratoma with some somatic malignant neoplasm component.
    • Monodermal teratoma.
  • Teratomas may also be classified based on the site:[4]
    • Intragonadal (ovary and testis).
    • Extragonadal (sacrococcygeal, retroperitoneum, mediastinum, and others).

References

  1. Zuquello RÁ, Tagliari G, Bagatini R, Camiña RH, Caron R, Lorencette NA; et al. (2016). "Immature teratoma presenting as a soft-tissue mass with no evidence of other sites of involvement: a case report". Diagn Pathol. 11 (1): 76. doi:10.1186/s13000-016-0527-x. PMC 4986345. PMID 27528018.
  2. Peterson, Christine M.; Buckley, Celine; Holley, Susan; Menias, Christine O. (2012). "Teratomas: A Multimodality Review". Current Problems in Diagnostic Radiology. 41 (6): 210–219. doi:10.1067/j.cpradiol.2012.02.001. ISSN 0363-0188.
  3. Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P; et al. (2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch Gynecol Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
  4. Varma AV, Malpani G, Agrawal P, Malukani K, Dosi S (2017). "Clinicopathological spectrum of teratomas: An 8-year retrospective study from a tertiary care institute". Indian J Cancer. 54 (3): 576–579. doi:10.4103/ijc.IJC_294_17. PMID 29798962.