Teratoma classification: Difference between revisions

Jump to navigation Jump to search
(33 intermediate revisions by 4 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Teratoma}}
{{Teratoma}}
{{CMG}} {{AE}} {{MD}}
{{CMG}} {{AE}} {{Mbt}}
 
==Classification==
==Classification==
* '''Childhood Extracranial Germ Cell Tumors classification'''
 
:* 1. GCTs arise from primordial germ cells, which migrate during embryogenesis from the yolk sac through the mesentery to the gonads.<ref name="pmid6343221">{{cite journal| author=Dehner LP| title=Gonadal and extragonadal germ cell neoplasia of childhood. | journal=Hum Pathol | year= 1983 | volume= 14 | issue= 6 | pages= 493-511 | pmid=6343221 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6343221  }} </ref><ref name="pmid18381640">{{cite journal| author=McIntyre A, Gilbert D, Goddard N, Looijenga L, Shipley J| title=Genes, chromosomes and the development of testicular germ cell tumors of adolescents and adults. | journal=Genes Chromosomes Cancer | year= 2008 | volume= 47 | issue= 7 | pages= 547-57 | pmid=18381640 | doi=10.1002/gcc.20562 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18381640  }} </ref> Childhood extracranial GCTs can be divided into the following two types:
:Teratomas are classifiable based on different general characteristics and site of origin.
:::* Gonadal.
:Historically teratomas was classified as :
:::* Extragonadal.
:* mature
:* 2. Most childhood extragonadal GCTs arise in midline sites (i.e., sacrococcygeal, mediastinal, and retroperitoneal); the midline location may represent aberrant embryonic migration of the primordial germ cells.Childhood extracranial GCTs are broadly classified as the following:
:* immature
:::* Mature teratomas.
In adults teratomas likely demonstrate malignant inclination and behavior. In Children, different tumors from various origins are reported, while predominantly we may see sacrococcygeal tumors. We can also classify teratomas to benign and malignant tumors. The malignant types are named teratocarcinomas.  Based on site of origin, teratomas are generally arise from ovary, testicle, or tailbone and less commonly from other areas.<ref name="urlTeratomas: A Multimodality Review - ScienceDirect">{{cite web |url=https://www.sciencedirect.com/science/article/abs/pii/S0363018812000151?via%3Dihub |title=Teratomas: A Multimodality Review - ScienceDirect |format= |work= |accessdate=}}</ref>
:::* Immature teratomas.
:::* Malignant GCTs.
:* 3. GCTs comprise a variety of histologic diagnoses and can also be divided into the following histologic types:
:::* Germinoma.
:::* Germinoma.
:::* Dysgerminoma (ovary).
:::* Seminoma (testis).
:::* Nongerminoma.
:::* Teratoma (mature and immature).
:::* Yolk sac tumor (endodermal sinus tumor).
:::* Choriocarcinoma.
:::* Embryonal carcinoma.
:::* Gonadoblastoma.
:::* Mixed GCT
:* 4. Pediatric GCT Biology
::* The following biologically distinct subtypes of GCTs are found in children and adolescents:
:::* Testicular GCTs.
:::* Ovarian GCTs.
:::* Extragonadal extracranial GCTs.


==References==
==References==
Line 40: Line 22:
[[Category:Pathology]]
[[Category:Pathology]]
[[Category:Surgery]]
[[Category:Surgery]]
[[Category:Oncology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]
[[Category:Pediatric cancers]]
[[Category:Pediatric cancers]]
[[Category:Endocrinology]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]

Revision as of 01:35, 16 September 2019

Teratoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Teratoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Staging

Laboratory Findings

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Teratoma classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Teratoma classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Teratoma classification

CDC on Teratoma classification

Teratoma classification in the news

Blogs on Teratoma classification

Directions to Hospitals Treating Teratoma

Risk calculators and risk factors for Teratoma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Masoud Bitarafan, M.D[[2]]

Classification

Teratomas are classifiable based on different general characteristics and site of origin.
Historically teratomas was classified as :
  • mature
  • immature

In adults teratomas likely demonstrate malignant inclination and behavior. In Children, different tumors from various origins are reported, while predominantly we may see sacrococcygeal tumors. We can also classify teratomas to benign and malignant tumors. The malignant types are named teratocarcinomas. Based on site of origin, teratomas are generally arise from ovary, testicle, or tailbone and less commonly from other areas.[1]

References

  1. "Teratomas: A Multimodality Review - ScienceDirect".