Takayasu's arteritis medical therapy
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Takayasu's arteritis Microchapters |
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Diagnosis |
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Treatment |
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Takayasu's arteritis medical therapy On the Web |
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Risk calculators and risk factors for Takayasu's arteritis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]
Overview
Medical Therapy
Medical therapy of Takayasu arteritis depends on the disease activity and the complications that develop.
The two most important aspects of treatment:
- Controlling the inflammatory process
- Controlling hypertension
Corticosteroids
- Corticosteroids are the mainstay of therapy for active Takayasu arteritis
- Most people with Takayasu’s arteritis respond to steroids such as prednisone
- The usual starting dose is approximately 1 milligram per kilogram of body weight per day
- Long-term, low-dose corticosteroid therapy may be required
- Osteoporosis prevention when patients are started on corticosteroids should be considered
IL-6 receptor inhibitor
- Humanized monoclonal antibody tocilizumab suggested as a treatment for Takayasu arteritis through blockade of the soluble interleukin-6 (IL-6) receptor.