Takayasu's arteritis history and symptoms: Difference between revisions

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* Subsequent pulseless phase
* Subsequent pulseless phase
** With progression of the disease and involvement of the branches of aorta, specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident
** With progression of the disease and involvement of the branches of [[aorta]], specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident.
** [[Subclavian artery]]: claudication in the upper extremities, subclavian steal syndrome
*** [[Subclavian artery]]:  
** Carotid and vertebral arteries: headache, vertigo, syncope, convulsions and dementia
**** claudication in the upper extremities, subclavian steal syndrome
** Coronary arteries: chest pain, angina which may progress to myocardial infarction
*** Carotid and vertebral arteries:
** Ascending aorta: aortic regurgiatation
**** Headache
**** Vertigo
**** Syncope
**** Convulsions
**** Dementia
*** Coronary arteries:
**** Chest pain
**** Angina which may progress to myocardial infarction
*** Ascending aorta:
**** Aortic regurgiatation


===Common Symptoms===
===Common Symptoms===
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* Ulcerated subacute nodular lesions (<2.5%)
* Ulcerated subacute nodular lesions (<2.5%)
* Pyoderma gangrenosum
* Pyoderma gangrenosum
* Angina
* Gastrointestinal symptoms


==References==
==References==

Revision as of 20:12, 31 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]


Overview

History

Takayasu's arteritis can be divided into two phases:[1]

  • Subsequent pulseless phase
    • With progression of the disease and involvement of the branches of aorta, specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident.
      • Subclavian artery:
        • claudication in the upper extremities, subclavian steal syndrome
      • Carotid and vertebral arteries:
        • Headache
        • Vertigo
        • Syncope
        • Convulsions
        • Dementia
      • Coronary arteries:
        • Chest pain
        • Angina which may progress to myocardial infarction
      • Ascending aorta:
        • Aortic regurgiatation

Common Symptoms

Common symptoms of Takayasu's arteritis include:

  • Headache
  • Malaise
  • Arthralgias
  • Bruit, with the most common location being the carotid artery (80%)
  • Blood pressure difference of extremities (45%-69%)
  • Claudication (38-81%)
  • Hypertension (28-53%; 58% with renal artery stenosis in one series
  • Visual disturbance

Less Common Symptoms

Less common symptoms of Takayasu's arteritis include:

  • Fever
  • Weight loss
  • Carotodynia or vessel tenderness
  • Raynaud syndrome
  • Stroke (5-9%)
  • Transient ischemic attacks (3-7%)
  • Seizures 
  • Erythema nodosum (6-19%)
  • Ulcerated subacute nodular lesions (<2.5%)
  • Pyoderma gangrenosum
  • Angina
  • Gastrointestinal symptoms

References

  1. Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (June 1994). "Takayasu arteritis". Ann. Intern. Med. 120 (11): 919–29. PMID 7909656.

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