TUBA1B: Difference between revisions
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'''Tubulin alpha-1B chain''' is a [[protein]] that in humans is encoded by the ''TUBA1B'' [[gene]].<ref name="pmid12054644">{{cite journal | author = Banerjee A | title = Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells | journal = Biochem Biophys Res Commun | volume = 293 | issue = 1 | pages = 598–601 |date=Jun 2002 | pmid = 12054644 | pmc = | doi = 10.1016/S0006-291X(02)00269-3 }}</ref><ref name="pmid6646120">{{cite journal |vauthors=Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW | title = Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions | journal = Mol Cell Biol | volume = 3 | issue = 10 | pages = 1738–45 |date=Jan 1984 | pmid = 6646120 | pmc = 370035 | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TUBA1B tubulin, alpha 1b| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10376| accessdate = }}</ref> | '''Tubulin alpha-1B chain''' is a [[protein]] that in humans is encoded by the ''TUBA1B'' [[gene]].<ref name="pmid12054644">{{cite journal | author = Banerjee A | title = Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells | journal = Biochem Biophys Res Commun | volume = 293 | issue = 1 | pages = 598–601 |date=Jun 2002 | pmid = 12054644 | pmc = | doi = 10.1016/S0006-291X(02)00269-3 }}</ref><ref name="pmid6646120">{{cite journal |vauthors=Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW | title = Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions | journal = Mol Cell Biol | volume = 3 | issue = 10 | pages = 1738–45 |date=Jan 1984 | pmid = 6646120 | pmc = 370035 | doi = 10.1128/mcb.3.10.1738}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TUBA1B tubulin, alpha 1b| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10376| accessdate = }}</ref> | ||
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*{{cite journal |vauthors=Kapeller R, Toker A, Cantley LC, Carpenter CL |title=Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin. |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25985–91 |year= 1995 |pmid= 7592789 |doi=10.1074/jbc.270.43.25985 }} | *{{cite journal |vauthors=Kapeller R, Toker A, Cantley LC, Carpenter CL |title=Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin. |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25985–91 |year= 1995 |pmid= 7592789 |doi=10.1074/jbc.270.43.25985 }} | ||
*{{cite journal |vauthors=Alexandrova N, Niklinski J, Bliskovsky V, etal |title=The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro. |journal=Mol. Cell. Biol. |volume=15 |issue= 9 |pages= 5188–95 |year= 1995 |pmid= 7651436 |doi= | pmc=230766 }} | *{{cite journal |vauthors=Alexandrova N, Niklinski J, Bliskovsky V, etal |title=The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro. |journal=Mol. Cell. Biol. |volume=15 |issue= 9 |pages= 5188–95 |year= 1995 |pmid= 7651436 |doi= | pmc=230766 }} | ||
*{{cite journal |vauthors=Szasz J, Yaffe MB, Sternlicht H |title=Site-directed mutagenesis of alpha-tubulin. Reductive methylation studies of the Lys 394 region. |journal=Biophys. J. |volume=64 |issue= 3 |pages= 792–802 |year= 1993 |pmid= 8097117 |doi=10.1016/S0006-3495(93)81440-1 | pmc=1262393 }} | *{{cite journal |vauthors=Szasz J, Yaffe MB, Sternlicht H |title=Site-directed mutagenesis of alpha-tubulin. Reductive methylation studies of the Lys 394 region. |journal=Biophys. J. |volume=64 |issue= 3 |pages= 792–802 |year= 1993 |pmid= 8097117 |doi=10.1016/S0006-3495(93)81440-1 | pmc=1262393 |bibcode=1993BpJ....64..792S }} | ||
*{{cite journal |vauthors=Baumann MH, Wisniewski T, Levy E, etal |title=C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type. |journal=Biochem. Biophys. Res. Commun. |volume=219 |issue= 1 |pages= 238–42 |year= 1996 |pmid= 8619814 |doi= 10.1006/bbrc.1996.0211 }} | *{{cite journal |vauthors=Baumann MH, Wisniewski T, Levy E, etal |title=C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type. |journal=Biochem. Biophys. Res. Commun. |volume=219 |issue= 1 |pages= 238–42 |year= 1996 |pmid= 8619814 |doi= 10.1006/bbrc.1996.0211 }} | ||
*{{cite journal |vauthors=Gress TM, Müller-Pillasch F, Geng M, etal |title=A pancreatic cancer-specific expression profile. |journal=Oncogene |volume=13 |issue= 8 |pages= 1819–30 |year= 1996 |pmid= 8895530 |doi= }} | *{{cite journal |vauthors=Gress TM, Müller-Pillasch F, Geng M, etal |title=A pancreatic cancer-specific expression profile. |journal=Oncogene |volume=13 |issue= 8 |pages= 1819–30 |year= 1996 |pmid= 8895530 |doi= }} | ||
Latest revision as of 19:18, 26 June 2018
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Tubulin alpha-1B chain is a protein that in humans is encoded by the TUBA1B gene.[1][2][3]
Interactions
TUBA1B has been shown to interact with PIK3R1.[4] Antibodies against tubulin alpha 1b can be used as markers for microtubules and spindles.[5]
References
- ↑ Banerjee A (Jun 2002). "Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells". Biochem Biophys Res Commun. 293 (1): 598–601. doi:10.1016/S0006-291X(02)00269-3. PMID 12054644.
- ↑ Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW (Jan 1984). "Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions". Mol Cell Biol. 3 (10): 1738–45. doi:10.1128/mcb.3.10.1738. PMC 370035. PMID 6646120.
- ↑ "Entrez Gene: TUBA1B tubulin, alpha 1b".
- ↑ Kapeller, R; Toker A; Cantley L C; Carpenter C L (Oct 1995). "Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin". J. Biol. Chem. UNITED STATES. 270 (43): 25985–91. doi:10.1074/jbc.270.43.25985. ISSN 0021-9258. PMID 7592789.
- ↑ http://www.genetex.com/WebPage/Product/PromotionDetail.aspx?Type=Promotion&PromotionID=178
Further reading
- Venter JC (1993). "Identification of new human receptor and transporter genes by high throughput cDNA (EST) sequencing". J. Pharm. Pharmacol. 45. Suppl 1: 355–60. PMID 8098743.
- Lopez-Fanarraga M, Avila J, Guasch A, et al. (2002). "Review: postchaperonin tubulin folding cofactors and their role in microtubule dynamics". J. Struct. Biol. 135 (2): 219–29. doi:10.1006/jsbi.2001.4386. PMID 11580271.
- Kapeller R, Toker A, Cantley LC, Carpenter CL (1995). "Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin". J. Biol. Chem. 270 (43): 25985–91. doi:10.1074/jbc.270.43.25985. PMID 7592789.
- Alexandrova N, Niklinski J, Bliskovsky V, et al. (1995). "The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro". Mol. Cell. Biol. 15 (9): 5188–95. PMC 230766. PMID 7651436.
- Szasz J, Yaffe MB, Sternlicht H (1993). "Site-directed mutagenesis of alpha-tubulin. Reductive methylation studies of the Lys 394 region". Biophys. J. 64 (3): 792–802. Bibcode:1993BpJ....64..792S. doi:10.1016/S0006-3495(93)81440-1. PMC 1262393. PMID 8097117.
- Baumann MH, Wisniewski T, Levy E, et al. (1996). "C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type". Biochem. Biophys. Res. Commun. 219 (1): 238–42. doi:10.1006/bbrc.1996.0211. PMID 8619814.
- Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
- Crépieux P, Kwon H, Leclerc N, et al. (1997). "I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain". Mol. Cell. Biol. 17 (12): 7375–85. PMC 232593. PMID 9372968.
- Herreros L, Rodríguez-Fernandez JL, Brown MC, et al. (2000). "Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton". J. Biol. Chem. 275 (34): 26436–40. doi:10.1074/jbc.M003970200. PMID 10840040.
- Watts NR, Sackett DL, Ward RD, et al. (2000). "HIV-1 rev depolymerizes microtubules to form stable bilayered rings". J. Cell Biol. 150 (2): 349–60. doi:10.1083/jcb.150.2.349. PMC 2180222. PMID 10908577.
- Takeoka A, Shimizu M, Horio T (2001). "Identification of an alpha-tubulin mutant of fission yeast from gamma-tubulin-interacting protein screening: genetic evidence for alpha-/gamma-tubulin interaction". J. Cell Sci. 113. Pt 24: 4557–62. PMID 11082048.
- Germani A, Bruzzoni-Giovanelli H, Fellous A, et al. (2001). "SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis". Oncogene. 19 (52): 5997–6006. doi:10.1038/sj.onc.1204002. PMID 11146551.
- Yokota S, Yanagi H, Yura T, Kubota H (2001). "Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle". Eur. J. Biochem. 268 (17): 4664–73. doi:10.1046/j.1432-1327.2001.02393.x. PMID 11532003.
- Rommelaere H, De Neve M, Neirynck K, et al. (2001). "Prefoldin recognition motifs in the nonhomologous proteins of the actin and tubulin families". J. Biol. Chem. 276 (44): 41023–8. doi:10.1074/jbc.M106591200. PMID 11535601.
- Klein C, Kramer EM, Cardine AM, et al. (2002). "Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau". J. Neurosci. 22 (3): 698–707. PMID 11826099.
- Saugstad JA, Yang S, Pohl J, et al. (2002). "Interaction between metabotropic glutamate receptor 7 and alpha tubulin". J. Neurochem. 80 (6): 980–8. doi:10.1046/j.0022-3042.2002.00778.x. PMC 2925652. PMID 11953448.
External links
- TUBA1B human gene location in the UCSC Genome Browser.
- TUBA1B human gene details in the UCSC Genome Browser.
 | This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it. |