TIAF1: Difference between revisions

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{{Infobox_gene}}
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'''TGFB1-induced anti-apoptotic factor 1''' is a [[protein]] that in humans is encoded by the ''TIAF1'' [[gene]].<ref name="pmid9918798">{{cite journal |vauthors=Chang NS, Mattison J, Cao H, Pratt N, Zhao Y, Lee C | title = Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity | journal = Biochem Biophys Res Commun | volume = 253 | issue = 3 | pages = 743–9 |date=February 1999 | pmid = 9918798 | pmc =  | doi = 10.1006/bbrc.1998.9846 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TIAF1 TGFB1-induced anti-apoptotic factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9220| accessdate = }}</ref>
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| image = 
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| PDB =
| Name = TGFB1-induced anti-apoptotic factor 1
| HGNCid = 11803
| Symbol = TIAF1
| AltSymbols =; MAJN; MYO18A; MYSPDZ; SPR210
| OMIM = 609517
| ECnumber = 
| Homologene = 
| MGIid = 
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003674 |text = molecular_function}} {{GNF_GO|id=GO:0003774 |text = motor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0016459 |text = myosin complex}}
  | Process = {{GNF_GO|id=GO:0006915 |text = apoptosis}} {{GNF_GO|id=GO:0006916 |text = anti-apoptosis}} {{GNF_GO|id=GO:0007249 |text = I-kappaB kinase/NF-kappaB cascade}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9220
    | Hs_Ensembl = 
    | Hs_RefseqProtein = NP_004731
    | Hs_RefseqmRNA = NM_004740
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
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    | Mm_GenLoc_chr = 
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'''TGFB1-induced anti-apoptotic factor 1''', also known as '''TIAF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TIAF1 TGFB1-induced anti-apoptotic factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9220| accessdate = }}</ref>


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==Interactions==
TIAF1 has been shown to [[Protein-protein interaction|interact]] with [[Janus kinase 3]]<ref name=pmid10733938>{{cite journal |last=Ji |first=H |authorlink= |author2=Zhai Q |author3=Zhu J |author4=Yan M |author5=Sun L |author6=Liu X |author7=Zheng Z  |date=April 2000  |title=A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival |journal=Biochem. Biophys. Res. Commun. |volume=270 |issue=1 |pages=267–71 |publisher= |location = UNITED STATES| issn = 0006-291X| pmid = 10733938 |doi = 10.1006/bbrc.2000.2413 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[TRIB3]].<ref name=pmid18276110>{{cite journal |last=Zhou |first=Ying |authorlink= |author2=Li Lu |author3=Liu Qiongming |author4=Xing Guichun |author5=Kuai Xuezhang |author6=Sun Jing |author7=Yin Xiushan |author8=Wang Jian |author9=Zhang Lingqiang |author10=He Fuchu  |date=May 2008 |title=E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3 |journal=Cell. Signal. |volume=20 |issue=5 |pages=942–8 |publisher= |location = England| issn = 0898-6568| pmid = 18276110 |doi = 10.1016/j.cellsig.2008.01.010 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321-9, 341-54 |year= 1997 |pmid= 9039502 |doi=  }}
*{{cite journal   |vauthors=Nagase T, Seki N, Ishikawa K, etal |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321–9, 341–54 |year= 1997 |pmid= 9039502 |doi=10.1093/dnares/3.5.321  }}
*{{cite journal  | author=Chang NS, Mattison J, Cao H, ''et al.'' |title=Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity. |journal=Biochem. Biophys. Res. Commun. |volume=253 |issue= 3 |pages= 743-9 |year= 1999 |pmid= 9918798 |doi= 10.1006/bbrc.1998.9846 }}
*{{cite journal   |vauthors=Ji H, Zhai Q, Zhu J, etal |title=A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival. |journal=Biochem. Biophys. Res. Commun. |volume=270 |issue= 1 |pages= 267–71 |year= 2000 |pmid= 10733938 |doi= 10.1006/bbrc.2000.2413 }}
*{{cite journal | author=Ji H, Zhai Q, Zhu J, ''et al.'' |title=A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival. |journal=Biochem. Biophys. Res. Commun. |volume=270 |issue= 1 |pages= 267-71 |year= 2000 |pmid= 10733938 |doi= 10.1006/bbrc.2000.2413 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Mori K, Furusawa T, Okubo T, etal |title=Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A). |journal=J. Biochem. |volume=133 |issue= 4 |pages= 405–13 |year= 2004 |pmid= 12761286 |doi=10.1093/jb/mvg053 }}
*{{cite journal | author=Mori K, Furusawa T, Okubo T, ''et al.'' |title=Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A). |journal=J. Biochem. |volume=133 |issue= 4 |pages= 405-13 |year= 2004 |pmid= 12761286 |doi=  }}
*{{cite journal   |vauthors=van der Leij J, van den Berg A, Albrecht EW, etal |title=High expression of TIAF-1 in chronic kidney and liver allograft rejection and in activated T-helper cells. |journal=Transplantation |volume=75 |issue= 12 |pages= 2076–82 |year= 2003 |pmid= 12829915 |doi= 10.1097/01.TP.0000069829.71088.88 }}
*{{cite journal | author=van der Leij J, van den Berg A, Albrecht EW, ''et al.'' |title=High expression of TIAF-1 in chronic kidney and liver allograft rejection and in activated T-helper cells. |journal=Transplantation |volume=75 |issue= 12 |pages= 2076-82 |year= 2003 |pmid= 12829915 |doi= 10.1097/01.TP.0000069829.71088.88 }}
*{{cite journal   |vauthors=Brajenovic M, Joberty G, Küster B, etal |title=Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12804–11 |year= 2004 |pmid= 14676191 |doi= 10.1074/jbc.M312171200 }}
*{{cite journal | author=Brajenovic M, Joberty G, Küster B, ''et al.'' |title=Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12804-11 |year= 2004 |pmid= 14676191 |doi= 10.1074/jbc.M312171200 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Bouwmeester T, Bauch A, Ruffner H, etal |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
*{{cite journal   |vauthors=Schultz L, Khera S, Sleve D, etal |title=TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53. |journal=DNA Cell Biol. |volume=23 |issue= 1 |pages= 67–74 |year= 2004 |pmid= 14965474 |doi= 10.1089/104454904322745943 }}
*{{cite journal | author=Schultz L, Khera S, Sleve D, ''et al.'' |title=TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53. |journal=DNA Cell Biol. |volume=23 |issue= 1 |pages= 67-74 |year= 2004 |pmid= 14965474 |doi= 10.1089/104454904322745943 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Homma K, Kikuno RF, Nagase T, etal |title=Alternative splice variants encoding unstable protein domains exist in the human brain. |journal=J. Mol. Biol. |volume=343 |issue= 5 |pages= 1207–20 |year= 2004 |pmid= 15491607 |doi= 10.1016/j.jmb.2004.09.028 }}
*{{cite journal | author=Homma K, Kikuno RF, Nagase T, ''et al.'' |title=Alternative splice variants encoding unstable protein domains exist in the human brain. |journal=J. Mol. Biol. |volume=343 |issue= 5 |pages= 1207-20 |year= 2004 |pmid= 15491607 |doi= 10.1016/j.jmb.2004.09.028 }}
*{{cite journal   |vauthors=Isogawa Y, Kon T, Inoue T, etal |title=The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site. |journal=Biochemistry |volume=44 |issue= 16 |pages= 6190–6 |year= 2005 |pmid= 15835906 |doi= 10.1021/bi0475931 }}
*{{cite journal | author=Isogawa Y, Kon T, Inoue T, ''et al.'' |title=The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site. |journal=Biochemistry |volume=44 |issue= 16 |pages= 6190-6 |year= 2005 |pmid= 15835906 |doi= 10.1021/bi0475931 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
}}
}}
{{refend}}
{{refend}}
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Revision as of 11:51, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

TGFB1-induced anti-apoptotic factor 1 is a protein that in humans is encoded by the TIAF1 gene.[1][2]


Interactions

TIAF1 has been shown to interact with Janus kinase 3[3] and TRIB3.[4]

References

  1. ↑ Chang NS, Mattison J, Cao H, Pratt N, Zhao Y, Lee C (February 1999). "Cloning and characterization of a novel transforming growth factor-beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity". Biochem Biophys Res Commun. 253 (3): 743–9. doi:10.1006/bbrc.1998.9846. PMID 9918798.
  2. ↑ "Entrez Gene: TIAF1 TGFB1-induced anti-apoptotic factor 1".
  3. ↑ Ji, H; Zhai Q; Zhu J; Yan M; Sun L; Liu X; Zheng Z (April 2000). "A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival". Biochem. Biophys. Res. Commun. UNITED STATES. 270 (1): 267–71. doi:10.1006/bbrc.2000.2413. ISSN 0006-291X. PMID 10733938.
  4. ↑ Zhou, Ying; Li Lu; Liu Qiongming; Xing Guichun; Kuai Xuezhang; Sun Jing; Yin Xiushan; Wang Jian; Zhang Lingqiang; He Fuchu (May 2008). "E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3". Cell. Signal. England. 20 (5): 942–8. doi:10.1016/j.cellsig.2008.01.010. ISSN 0898-6568. PMID 18276110.

Further reading



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