Sulfate adenylyltransferase (ADP)

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In enzymology, a sulfate adenylyltransferase (ADP) (EC is an enzyme that catalyzes the chemical reaction

ADP + sulfate phosphate + adenylyl sulfate

Thus, the two substrates of this enzyme are ADP and sulfate, whereas its two products are phosphate and adenylyl sulfate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:sulfate adenylyltransferase. Other names in common use include ADP-sulfurylase, sulfate (adenosine diphosphate) adenylyltransferase, and adenosine diphosphate sulfurylase. This enzyme participates in sulfur metabolism.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Grunberg-Manago M, Del Campillo-Campbell A, Dondon L, Michelson AM (1966). "[Yeast ADP-sulfurylase catalyzing an exchange between orthophosphate and the terminal phosphate of nucleoside diphosphates]". Biochim. Biophys. Acta. 123: 1&ndash, 16. PMID 5964041.
  • ROBBINS PW, LIPMANN F (1957). "Isolation and identification of active sulfate". J. Biol. Chem. 229: 837&ndash, 51. PMID 13502346.

External links

The CAS registry number for this enzyme class is 9027-70-7.

Gene Ontology (GO) codes