Subependymal giant cell astrocytoma natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
*Poor prognostic factors for subependymal giant cell astrocytoma include:<ref name="RothRoach2013">{{cite journal|last1=Roth|first1=Jonathan|last2=Roach|first2=E. Steve|last3=Bartels|first3=Ute|last4=Jóźwiak|first4=Sergiusz|last5=Koenig|first5=Mary Kay|last6=Weiner|first6=Howard L.|last7=Franz|first7=David N.|last8=Wang|first8=Henry Z.|title=Subependymal Giant Cell Astrocytoma: Diagnosis, Screening, and Treatment. Recommendations From the International Tuberous Sclerosis Complex Consensus Conference 2012|journal=Pediatric Neurology|volume=49|issue=6|year=2013|pages=439–444|issn=08878994|doi=10.1016/j.pediatrneurol.2013.08.017}}</ref> | |||
:*Invasion to neighboring structures ([[fornix of brain|fornix]], [[hypothalamus]], [[basal gangli]]a, or [[genu of internal capsule]]) | |||
:*Large sized tumors | |||
:*Recurrent tumors | |||
==Reference== | ==Reference== |
Revision as of 23:17, 2 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Natural History
- Subependymal giant cell astrocytoma tends to grow slowly and are less likely to spread.[1]
- If left untreated, patients with subependymal giant cell astrocytoma may progress to cause occlusion of the foramen of Monro, cerebral aqueduct (of Sylvius), third ventricle, or fourth ventricle, with subsequent elevated intracranial pressure and obstructive hydrocephalus, thus necessitating intervention.[2]
Complication
Common complications of subependymal giant cell astrocytoma include:
Prognosis
- Poor prognostic factors for subependymal giant cell astrocytoma include:[1]
- Invasion to neighboring structures (fornix, hypothalamus, basal ganglia, or genu of internal capsule)
- Large sized tumors
- Recurrent tumors
Reference
- ↑ 1.0 1.1 Roth, Jonathan; Roach, E. Steve; Bartels, Ute; Jóźwiak, Sergiusz; Koenig, Mary Kay; Weiner, Howard L.; Franz, David N.; Wang, Henry Z. (2013). "Subependymal Giant Cell Astrocytoma: Diagnosis, Screening, and Treatment. Recommendations From the International Tuberous Sclerosis Complex Consensus Conference 2012". Pediatric Neurology. 49 (6): 439–444. doi:10.1016/j.pediatrneurol.2013.08.017. ISSN 0887-8994.
- ↑ Clinical presentation of subependymal giant cell astrocytoma. Dr. Bruno Di Muzio and Dr. Jeremy Jones et al. Radiopaedia 2015. http://radiopaedia.org/articles/subependymal-giant-cell-astrocytoma. Accessed on November 2, 2015