Struma ovarii laboratory findings: Difference between revisions

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==Laboratory Findings==
==Laboratory Findings==
*Struma ovarii can be diagnosed only based on [[histopathologic]] <nowiki/>studies. <ref name="pmid24783110">{{cite journal |vauthors=Sinha NK |title=Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary |journal=J Clin Diagn Res |volume=8 |issue=3 |pages=140–1 |year=2014 |pmid=24783110 |pmc=4003614 |doi=10.7860/JCDR/2014/8005.4138 |url=}}</ref>
*Struma ovarii can be diagnosed only based on [[histopathologic]] <nowiki/>studies. <ref name="pmid24783110">{{cite journal |vauthors=Sinha NK |title=Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary |journal=J Clin Diagn Res |volume=8 |issue=3 |pages=140–1 |year=2014 |pmid=24783110 |pmc=4003614 |doi=10.7860/JCDR/2014/8005.4138 |url=}}</ref>
*[[Radiological]] findings, [[ascites]] and raised [[CA-125]] levels make it a unique and highly suspicious case of [[malignancy]]. <ref name="pmid27355004">{{cite journal |vauthors=Oudoux A, Leblanc E, Beaujot J, Gauthier-Kolesnikov H |title=Treatment and follow-up of malignant struma ovarii: Regarding two cases |journal=Gynecol Oncol Rep |volume=17 |issue= |pages=56–9 |year=2016 |pmid=27355004 |pmc=4913172 |doi=10.1016/j.gore.2016.05.014 |url=}}</ref><ref name="pmid24783110">{{cite journal |vauthors=Sinha NK |title=Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary |journal=J Clin Diagn Res |volume=8 |issue=3 |pages=140–1 |year=2014 |pmid=24783110 |pmc=4003614 |doi=10.7860/JCDR/2014/8005.4138 |url=}}</ref>
*[[Histopathologic]] studies may aid in diagnosing the [[malignant]] struma ovarii when there is no evidence of clinical [[malignancy]] or [[metastases]]. <ref name="pmid12172581">{{cite journal| author=Kabukcuoglu F, Baksu A, Yilmaz B, Aktumen A, Evren I| title=Malignant struma ovarii. | journal=Pathol Oncol Res | year= 2002 | volume= 8 | issue= 2 | pages= 145-7 | pmid=12172581 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12172581  }} </ref>
*Elevated levels of [[CA-125]] has been reported rarely in approximately only 8-10 of cases so far. <ref name="pmid18334015">{{cite journal |vauthors=Mitrou S, Manek S, Kehoe S |title=Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature |journal=Int. J. Gynecol. Cancer |volume=18 |issue=2 |pages=372–5 |year=2008 |pmid=18334015 |doi=10.1111/j.1525-1438.2007.00998.x |url=}}</ref><ref name="pmid4003614">{{cite journal |vauthors=Boselie F, Leeuwenberg E |title=Birkhoff revisited: beauty as a function of effect and means |journal=Am J Psychol |volume=98 |issue=1 |pages=1–39 |year=1985 |pmid=4003614 |doi= |url=}}</ref>
*Elevated levels of [[CA-125]] has been reported rarely in approximately only 8-10 of cases so far. <ref name="pmid18334015">{{cite journal |vauthors=Mitrou S, Manek S, Kehoe S |title=Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature |journal=Int. J. Gynecol. Cancer |volume=18 |issue=2 |pages=372–5 |year=2008 |pmid=18334015 |doi=10.1111/j.1525-1438.2007.00998.x |url=}}</ref><ref name="pmid4003614">{{cite journal |vauthors=Boselie F, Leeuwenberg E |title=Birkhoff revisited: beauty as a function of effect and means |journal=Am J Psychol |volume=98 |issue=1 |pages=1–39 |year=1985 |pmid=4003614 |doi= |url=}}</ref>
*In cases of metastatic struma ovarii post total [[thyroidectomy]] along with [[radioiodine]] scanning and [[radioiodine]] ablation, the [[thyroglobulin]] levels must be monitored as a [[tumor marker]], and diagnostic [[radioiodine]] scans should be done to screen for residual or recurrent disease. <ref name="pmid19289330">{{cite journal| author=McGill JF, Sturgeon C, Angelos P| title=Metastatic struma ovarii treated with total thyroidectomy and radioiodine ablation. | journal=Endocr Pract | year= 2009 | volume= 15 | issue= 2 | pages= 167-73 | pmid=19289330 | doi=10.4158/EP.15.2.167 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19289330  }} </ref>
*In cases of metastatic struma ovarii post total [[thyroidectomy]] along with [[radioiodine]] scanning and [[radioiodine]] ablation, the [[thyroglobulin]] levels must be monitored as a [[tumor marker]], and diagnostic [[radioiodine]] scans should be done to screen for residual or recurrent disease. <ref name="pmid19289330">{{cite journal| author=McGill JF, Sturgeon C, Angelos P| title=Metastatic struma ovarii treated with total thyroidectomy and radioiodine ablation. | journal=Endocr Pract | year= 2009 | volume= 15 | issue= 2 | pages= 167-73 | pmid=19289330 | doi=10.4158/EP.15.2.167 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19289330  }} </ref>

Latest revision as of 00:37, 16 October 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

Laboratory findings consistent with the diagnosis of struma ovarii include histopathologic studies and elevated CA-125 levels.

Laboratory Findings

References

  1. 1.0 1.1 Sinha NK (2014). "Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary". J Clin Diagn Res. 8 (3): 140–1. doi:10.7860/JCDR/2014/8005.4138. PMC 4003614. PMID 24783110.
  2. Mitrou S, Manek S, Kehoe S (2008). "Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature". Int. J. Gynecol. Cancer. 18 (2): 372–5. doi:10.1111/j.1525-1438.2007.00998.x. PMID 18334015.
  3. Boselie F, Leeuwenberg E (1985). "Birkhoff revisited: beauty as a function of effect and means". Am J Psychol. 98 (1): 1–39. PMID 4003614.
  4. McGill JF, Sturgeon C, Angelos P (2009). "Metastatic struma ovarii treated with total thyroidectomy and radioiodine ablation". Endocr Pract. 15 (2): 167–73. doi:10.4158/EP.15.2.167. PMID 19289330.
  5. Volpi E, Ferrero A, Nasi PG, Sismondi P (2003). "Malignant struma ovarii: a case report of laparoscopic management". Gynecol. Oncol. 90 (1): 191–4. PMID 12821363.
  6. Zekri JM, Manifold IH, Wadsley JC (2006). "Metastatic struma ovarii: late presentation, unusual features and multiple radioactive iodine treatments". Clin Oncol (R Coll Radiol). 18 (10): 768–72. PMID 17168212.
  7. Balci TA, Kabasakal L (2005). "Is the I-131 whole-body scanning proper for follow-up management of the patients with malignant struma ovarii without performing the thyroidectomy?". Gynecol. Oncol. 99 (2): 520. doi:10.1016/j.ygyno.2005.04.017. PMID 15963556.

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