Struma ovarii laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of Struma ovarii include histopathologic studies and | Laboratory findings consistent with the diagnosis of Struma ovarii include histopathologic studies and elevated [[CA-125]] levels. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Revision as of 15:20, 22 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
Laboratory findings consistent with the diagnosis of Struma ovarii include histopathologic studies and elevated CA-125 levels.
Laboratory Findings
- Struma ovarii can be diagnosed only based on histopathologic studies. [1]
- Radiological findings, ascites and raised CA 125 levels make it a unique and highly suspicious case of malignancy. [2] [1]
- Histopathologic studies may aid in diagnosing the malignant struma ovarii when there is no evidence of clinical malignancy or metastases. [3]
- Elevated levels of CA 125 has been reported rarely in approximately only 8-10 cases so far. [4] [5]
- In cases of metastatic struma ovarii post total thyroidectomy along with radioiodine scanning and radioiodine ablation, the thyroglobulin levels must be monitored as a tumor marker, and diagnostic radioiodine scans should be done to screen for residual or recurrent disease. [6]
- For follow-up as a marker of recurrence, serum thyroglobulin levels and I131 scan may be used. [7] [8] [1]
- The I131 scan or thyroglobulin have no aid in the follow-up if thyroidectomy is not performed. [9]
References
- ↑ 1.0 1.1 1.2 Sinha NK (2014). "Struma ovarii with elevated ca-125 levels and ascites mimicking advanced ca ovary". J Clin Diagn Res. 8 (3): 140–1. doi:10.7860/JCDR/2014/8005.4138. PMC 4003614. PMID 24783110.
- ↑ Oudoux A, Leblanc E, Beaujot J, Gauthier-Kolesnikov H (2016). "Treatment and follow-up of malignant struma ovarii: Regarding two cases". Gynecol Oncol Rep. 17: 56–9. doi:10.1016/j.gore.2016.05.014. PMC 4913172. PMID 27355004.
- ↑ Kabukcuoglu F, Baksu A, Yilmaz B, Aktumen A, Evren I (2002). "Malignant struma ovarii". Pathol. Oncol. Res. 8 (2): 145–7. doi:PAOR.2002.8.2.0145 Check
|doi=value (help). PMID 12172581. - ↑ Mitrou S, Manek S, Kehoe S (2008). "Cystic struma ovarii presenting as pseudo-Meigs' syndrome with elevated CA125 levels. A case report and review of the literature". Int. J. Gynecol. Cancer. 18 (2): 372–5. doi:10.1111/j.1525-1438.2007.00998.x. PMID 18334015.
- ↑ Boselie F, Leeuwenberg E (1985). "Birkhoff revisited: beauty as a function of effect and means". Am J Psychol. 98 (1): 1–39. PMID 4003614.
- ↑ McGill JF, Sturgeon C, Angelos P (2009). "Metastatic struma ovarii treated with total thyroidectomy and radioiodine ablation". Endocr Pract. 15 (2): 167–73. doi:10.4158/EP.15.2.167. PMID 19289330.
- ↑ Volpi E, Ferrero A, Nasi PG, Sismondi P (2003). "Malignant struma ovarii: a case report of laparoscopic management". Gynecol. Oncol. 90 (1): 191–4. PMID 12821363.
- ↑ Zekri JM, Manifold IH, Wadsley JC (2006). "Metastatic struma ovarii: late presentation, unusual features and multiple radioactive iodine treatments". Clin Oncol (R Coll Radiol). 18 (10): 768–72. PMID 17168212.
- ↑ Balci TA, Kabasakal L (2005). "Is the I-131 whole-body scanning proper for follow-up management of the patients with malignant struma ovarii without performing the thyroidectomy?". Gynecol. Oncol. 99 (2): 520. doi:10.1016/j.ygyno.2005.04.017. PMID 15963556.