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==Medical therapy==
==Medical therapy==
The mainstay of therapy for Strep throat is medical therapy. Treatment will help reduce symptoms, minimize transmission, and reduce the likelihood of complications. Antibiotic treatment recommended for strep throat include the following:  
The mainstay of therapy for Strep throat is medical therapy. Treatment will help reduce symptoms, minimize transmission, and reduce the likelihood of complications. Antibiotic treatment recommended for strep throat include the following:  


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{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
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| style="padding: 5px 5px; background: #DCDCDC;" | '''Penicillin V, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Penicillin V, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Children: 250 mg twice daily or 3 times daily; adolescents and adults: 250 mg 4 times daily or 500 mg twice daily
Children: 250 mg twice daily or 3 times daily; adolescents and adults: 250 mg 4 times daily or 500 mg twice daily
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |'''Amoxicillin, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" |'''Amoxicillin, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*50 mg/kg once daily (max = 1000 mg);  
50 mg/kg once daily (max = 1000 mg);  
*Alternate:25 mg/kg (max = 500 mg) twice daily
Alternate:25 mg/kg (max = 500 mg) twice daily
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" |'''Benzathine penicillin G, intramuscular'''
| style="padding: 5px 5px; background: #DCDCDC;" |'''Benzathine penicillin G, intramuscular'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*<27 kg: 600 000 U; ≥27 kg: 1 200 000 U
<27 kg: 600 000 U; ≥27 kg: 1 200 000 U
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*1 dose
1 dose
|-
|-
| colspan="3" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|'''For individuals with penicillin allergy'''}}
| colspan="3" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|'''For individuals with penicillin allergy'''}}
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| style="padding: 5px 5px; background: #DCDCDC;" | '''Cephalexin, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Cephalexin, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*20 mg/kg/dose twice daily (max = 500 mg/dose)
20 mg/kg/dose twice daily (max = 500 mg/dose)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''Cefadroxil, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Cefadroxil, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*30 mg/kg once daily (max = 1 g)
30 mg/kg once daily (max = 1 g)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''Clindamycin, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Clindamycin, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*7 mg/kg/dose 3 times daily (max = 300 mg/dose)
7 mg/kg/dose 3 times daily (max = 300 mg/dose)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''Azithromycin, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Azithromycin, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*12 mg/kg once daily (max = 500 mg)
12 mg/kg once daily (max = 500 mg)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*5 days
5 days
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;" | '''Clarithromycin, oral'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Clarithromycin, oral'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*7.5 mg/kg/dose twice daily (max = 250 mg/dose)
7.5 mg/kg/dose twice daily (max = 250 mg/dose)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*10 days
10 days
|-
|-
|}
|}


==References==
==References==

Revision as of 19:43, 18 October 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

Medical therapy

The mainstay of therapy for Strep throat is medical therapy. Treatment will help reduce symptoms, minimize transmission, and reduce the likelihood of complications. Antibiotic treatment recommended for strep throat include the following:

For individuals without penicillin allergy
Drug, Route Recommended dose Duration
Penicillin V, oral

Children: 250 mg twice daily or 3 times daily; adolescents and adults: 250 mg 4 times daily or 500 mg twice daily

10 days

Amoxicillin, oral

50 mg/kg once daily (max = 1000 mg); Alternate:25 mg/kg (max = 500 mg) twice daily

10 days

Benzathine penicillin G, intramuscular

<27 kg: 600 000 U; ≥27 kg: 1 200 000 U

1 dose

For individuals with penicillin allergy
Cephalexin, oral

20 mg/kg/dose twice daily (max = 500 mg/dose)

10 days

Cefadroxil, oral

30 mg/kg once daily (max = 1 g)

10 days

Clindamycin, oral

7 mg/kg/dose 3 times daily (max = 300 mg/dose)

10 days

Azithromycin, oral

12 mg/kg once daily (max = 500 mg)

5 days

Clarithromycin, oral

7.5 mg/kg/dose twice daily (max = 250 mg/dose)

10 days

References


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