Steroid

Revision as of 18:20, 27 September 2011 by WikiBot (talk | contribs) (Protected "Steroid": Protecting pages from unwanted edits ([edit=sysop] (indefinite) [move=sysop] (indefinite)))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
Steroid skeleton of lanosterol. The total number of carbons (30) reflects its triterpenoid origin. In some steroids some carbons may be removed (such as carbon 18) or added (such as carbons 241 and 242) in downstream biosynthetic reactions.

WikiDoc Resources for Steroid

Articles

Most recent articles on Steroid

Most cited articles on Steroid

Review articles on Steroid

Articles on Steroid in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Steroid

Images of Steroid

Photos of Steroid

Podcasts & MP3s on Steroid

Videos on Steroid

Evidence Based Medicine

Cochrane Collaboration on Steroid

Bandolier on Steroid

TRIP on Steroid

Clinical Trials

Ongoing Trials on Steroid at Clinical Trials.gov

Trial results on Steroid

Clinical Trials on Steroid at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Steroid

NICE Guidance on Steroid

NHS PRODIGY Guidance

FDA on Steroid

CDC on Steroid

Books

Books on Steroid

News

Steroid in the news

Be alerted to news on Steroid

News trends on Steroid

Commentary

Blogs on Steroid

Definitions

Definitions of Steroid

Patient Resources / Community

Patient resources on Steroid

Discussion groups on Steroid

Patient Handouts on Steroid

Directions to Hospitals Treating Steroid

Risk calculators and risk factors for Steroid

Healthcare Provider Resources

Symptoms of Steroid

Causes & Risk Factors for Steroid

Diagnostic studies for Steroid

Treatment of Steroid

Continuing Medical Education (CME)

CME Programs on Steroid

International

Steroid en Espanol

Steroid en Francais

Business

Steroid in the Marketplace

Patents on Steroid

Experimental / Informatics

List of terms related to Steroid

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

A steroid is a terpenoid lipid characterized by a carbon skeleton with four fused rings, generally arranged in a 6-6-6-5 fashion.

Steroids can vary by the functional groups attached to these rings and the oxidation state of the rings. Hundreds of distinct steroids are found in plants, animals, and fungi. All steroids are biosynthetically derived either from the sterol lanosterol (animals and fungi) or the sterol cycloartenol (plants). Both sterols are derived from the cyclization of the triterpene squalene.[1]

Origin

Simplified version of the steroid synthesis pathway with the intermediates isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP) and squalene shown. Some intermediates are omitted.

Steroids include estrogen (US spelling) or oestrogen (UK/AUS spelling), progesterone and testosterone. Oestrogen and progesterone are made primarily in the ovary and in the placenta during pregnancy and testosterone in the testes. Certain neurons and glia in the central nervous system (CNS) express the enzymes that are required for the local synthesis of pregnane neurosteroids, either de novo or from peripherally derived sources.

Classification

Taxonomical/Functional

Some of the common categories of steroids:

Structural

It is also possible to classify steroids based upon their chemical composition.

See Also

References

Template:Steroids

bg:Стероид ca:Esteroide cs:Steroidy de:Steroide eo:Steroido ko:스테로이드 it:Steroide he:סטרואיד nl:Steroïde no:Steroid simple:Steroid sk:Steroid sr:Стероиди fi:Steroidi sv:Steroid th:สเตอรอยด์


Template:WikiDoc Sources