Steatorrhea natural history, complications and prognosis: Difference between revisions

	Steatorrhea Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Steatorrhea from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Steatorrhea natural history, complications and prognosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Steatorrhea natural history, complications and prognosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Steatorrhea natural history, complications and prognosis
CDC on Steatorrhea natural history, complications and prognosis
Steatorrhea natural history, complications and prognosis in the news
Blogs on Steatorrhea natural history, complications and prognosis
Directions to Hospitals Treating Steatorrhea
Risk calculators and risk factors for Steatorrhea natural history, complications and prognosis

VisualWikitext

Latest revision as of 18:03, 20 February 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]Sunny Kumar MD [3]

Overview

If left untreated, steatorrhea can lead to severe malnutrition due to inability of gastrointestinal tract to absorb fat soluble vitamins and ultimately severe weight loss. Complication of steatorrhea include anemia, intestinal obstruction, weight loss. Prognosis of steatorrhea is generally good with appropriate treatment.

Natural History

If left untreated, steatorrhea can lead to severe malnutrition due to inability of gastrointestinal tract to absorb fat soluble vitamins and ultimately severe weight loss.atorrhea:^[1]^[2]^[3]

Complications

Complication of steatorrhea include:^[4]^[5]

Adults

Children

Prognosis

Prognosis of steatorrhea is generally good with appropriate treatment.

References

↑ Scarpignato C, Gatta L, Zullo A, Blandizzi C, SIF-AIGO-FIMMG Group. Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners (2016). "Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression". BMC Med. 14 (1): 179. doi:10.1186/s12916-016-0718-z. PMC 5101793. PMID 27825371.
↑ Podboy A, Anderson BW, Sweetser S (2016). "61-Year-Old Man With Chronic Diarrhea". Mayo Clin Proc. 91 (2): e23–8. doi:10.1016/j.mayocp.2015.07.033. PMID 26769182.
↑ Burnett JR, Hooper AJ (2015). "Vitamin E and oxidative stress in abetalipoproteinemia and familial hypobetalipoproteinemia". Free Radic Biol Med. 88 (Pt A): 59–62. doi:10.1016/j.freeradbiomed.2015.05.044. PMID 26086616.
↑ Valenzise M, Alessi L, Bruno E, Cama V, Costanzo D, Genovese C; et al. (2016). "APECED syndrome in childhood: clinical spectrum is enlarging". Minerva Pediatr. 68 (3): 226–9. PMID 25502918.
↑ Wilcox C, Turner J, Green J (2014). "Systematic review: the management of chronic diarrhoea due to bile acid malabsorption". Aliment Pharmacol Ther. 39 (9): 923–39. doi:10.1111/apt.12684. PMID 24602022.

Template:WS Template:WH

[pmid278253712-1] Scarpignato C, Gatta L, Zullo A, Blandizzi C, SIF-AIGO-FIMMG Group. Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners (2016). "Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression". BMC Med. 14 (1): 179. doi:10.1186/s12916-016-0718-z. PMC 5101793. PMID 27825371.

[pmid267691822-2] Podboy A, Anderson BW, Sweetser S (2016). "61-Year-Old Man With Chronic Diarrhea". Mayo Clin Proc. 91 (2): e23–8. doi:10.1016/j.mayocp.2015.07.033. PMID 26769182.

[pmid260866162-3] Burnett JR, Hooper AJ (2015). "Vitamin E and oxidative stress in abetalipoproteinemia and familial hypobetalipoproteinemia". Free Radic Biol Med. 88 (Pt A): 59–62. doi:10.1016/j.freeradbiomed.2015.05.044. PMID 26086616.

[pmid255029182-4] Valenzise M, Alessi L, Bruno E, Cama V, Costanzo D, Genovese C; et al. (2016). "APECED syndrome in childhood: clinical spectrum is enlarging". Minerva Pediatr. 68 (3): 226–9. PMID 25502918.

[pmid246020223-5] Wilcox C, Turner J, Green J (2014). "Systematic review: the management of chronic diarrhoea due to bile acid malabsorption". Aliment Pharmacol Ther. 39 (9): 923–39. doi:10.1111/apt.12684. PMID 24602022.

[1]

[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Steatorrhea}}
-{{CMG}}; {{AE}}{{Vbe}}
+{{CMG}}; {{AE}}{{Vbe}}{{SKA}}
 == Overview ==
-Steatorrhea on long term basis leads to deficiency of important nutrients. These deficiency ultimately effect body functions.
+If left untreated, steatorrhea can lead to severe malnutrition due to inability of gastrointestinal tract to absorb fat soluble vitamins and  ultimately severe weight loss. Complication of steatorrhea include [[anemia]], [[intestinal obstruction]], [[weight loss]]. Prognosis of steatorrhea is generally good with appropriate treatment.
 == Natural History ==
-The importance for the parthenogenesis of steatorrhea is deficiency of enzymes required for digestion of fatty food, or absorption of digested fatty food. The mechanism may be different for patients having steatorrhea and the microscopic picture of every pathology may be different but the effect of loosing fat in stool is similar in all patients. Steatorrhea was caused by the decreased enzymatic function of the pancreas, asynchronism of the food and bile supply to the intestinal lumen, disorders of absorption of lipolysis products.
+If left untreated, steatorrhea can lead to severe malnutrition due to inability of gastrointestinal tract to absorb fat soluble vitamins and  ultimately severe weight loss.[[Steatorrhea|atorrhea]]:<ref name="pmid278253712">{{cite journal| author=Scarpignato C, Gatta L, Zullo A, Blandizzi C, SIF-AIGO-FIMMG Group. Italian Society of Pharmacology, the Italian Association of Hospital Gastroenterologists, and the Italian Federation of General Practitioners| title=Effective and safe proton pump inhibitor therapy in acid-related diseases - A position paper addressing benefits and potential harms of acid suppression. | journal=BMC Med | year= 2016 | volume= 14 | issue= 1 | pages= 179 | pmid=27825371 | doi=10.1186/s12916-016-0718-z | pmc=5101793 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27825371  }}</ref><ref name="pmid267691822">{{cite journal| author=Podboy A, Anderson BW, Sweetser S| title=61-Year-Old Man With Chronic Diarrhea. | journal=Mayo Clin Proc | year= 2016 | volume= 91 | issue= 2 | pages= e23-8 | pmid=26769182 | doi=10.1016/j.mayocp.2015.07.033 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26769182  }}</ref><ref name="pmid260866162">{{cite journal| author=Burnett JR, Hooper AJ| title=Vitamin E and oxidative stress in abetalipoproteinemia and familial hypobetalipoproteinemia. | journal=Free Radic Biol Med | year= 2015 | volume= 88 | issue= Pt A | pages= 59-62 | pmid=26086616 | doi=10.1016/j.freeradbiomed.2015.05.044 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26086616  }}</ref>
-These are the main causes that can lead to the appearance of steatorrhea:
-Inadequate production of bile (bile acids lacking)
-Liver damage
-Medication to reduce the level of lipids in the blood (hypolipidemic)
-Surgical removal of gallbladder (cholecystectomy)
-Pancreatic enzyme defect
-Defect at the level of the mucosal cells
-Medication that has as purpose the blockage of fat absorption
-Fat rich diet (indigestible or excess oils in the diet might cause similar problems)
-Acromegaly treatment as Somatostatin analogues – octreotide, lanreotide (adverse effect)
-Eating nuts in large quantities (such as cashews)
-Jojoba oil (indigestible oil)
-Escolar/oilfish consumption
-Consumption of artificial fats.
 == Complications ==
-The outcomes of steatorrhea are explained as below:
+Complication of steatorrhea include:<ref name="pmid255029182">{{cite journal| author=Valenzise M, Alessi L, Bruno E, Cama V, Costanzo D, Genovese C et al.| title=APECED syndrome in childhood: clinical spectrum is enlarging. | journal=Minerva Pediatr | year= 2016 | volume= 68 | issue= 3 | pages= 226-9 | pmid=25502918 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25502918  }}</ref><ref name="pmid246020223">{{cite journal| author=Wilcox C, Turner J, Green J| title=Systematic review: the management of chronic diarrhoea due to bile acid malabsorption. | journal=Aliment Pharmacol Ther | year= 2014 | volume= 39 | issue= 9 | pages= 923-39 | pmid=24602022 | doi=10.1111/apt.12684 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24602022  }}</ref>
+* Adults
-Adults:
+** [[Anemia]]
+** [[Intestinal obstruction]]
-Anemia,
+** [[Weight loss]]
-Intestinal obstruction
-Weight loss.
-Children:
- Failure to thrive
-Anemia
-Weight loss
+* Children
+** [[Failure to thrive]]
+** [[Anemia]]
+** [[Weight loss]]
 == Prognosis ==
-Prognosis generaly is good once the cause are treated and if replacement therapy is started . Most of the time it depend on the the cause of loosing fat in stool.
+Prognosis of steatorrhea is generally good with appropriate treatment.
 ==References==