Squamous cell carcinoma of the skin medical therapy: Difference between revisions
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== Medical Treatment == | == Medical Treatment == | ||
Medical care of [[Squamous cell carcinoma]] includes cryosurgery, electrosurgery, topical treatment for cutaneous lesions and Radiation therapy and Chemotherapy for systemic disease. | Medical care of [[Squamous cell carcinoma]] (SCC) includes cryosurgery, electrosurgery, topical treatment for cutaneous lesions and Radiation therapy and Chemotherapy for systemic disease. | ||
* [[Cryotherapy]] destroys malignant cells by freezing and thawing. It is useful for small, well-defined, low-risk invasive SCCs and for Bowen's disease. In cryosurgery, liquid nitrogen is applied to the tumor and a surrounding rim of normal-appearing skin (usually ≥3 mm). The frozen area is then allowed to thaw unaided. In most cases, the tumor is refrozen to complete two freeze-thaw cycles; for Bowen's disease, a single freeze-thaw cycle may be sufficient.<ref>{{cite journal |author=Holt PJ |title=Cryotherapy for skin cancer: results over a 5-year period using liquid nitrogen spray cryosurgery |journal=Br. J. Dermatol. |volume=119 |issue=2 |pages=231–40 |year=1988 |month=August |pmid=3166941 |doi= |url=}}</ref>.Tumor cell death is due to the formation of intra and extracellular ice crystals, hypertonicity, disruption of the phospholipid membrane, and vascular stasis. Cryotherapy is a quick procedure and is cost-effective. | * [[Cryotherapy]] destroys malignant cells by freezing and thawing. It is useful for small, well-defined, low-risk invasive SCCs and for Bowen's disease. In cryosurgery, liquid nitrogen is applied to the tumor and a surrounding rim of normal-appearing skin (usually ≥3 mm). The frozen area is then allowed to thaw unaided. In most cases, the tumor is refrozen to complete two freeze-thaw cycles; for Bowen's disease, a single freeze-thaw cycle may be sufficient.<ref>{{cite journal |author=Holt PJ |title=Cryotherapy for skin cancer: results over a 5-year period using liquid nitrogen spray cryosurgery |journal=Br. J. Dermatol. |volume=119 |issue=2 |pages=231–40 |year=1988 |month=August |pmid=3166941 |doi= |url=}}</ref>.Tumor cell death is due to the formation of intra and extracellular ice crystals, hypertonicity, disruption of the phospholipid membrane, and vascular stasis. Cryotherapy is a quick procedure and is cost-effective. This therapy is not indicated for large recurrent lesions,deeply invasive and other high risk SCC. | ||
==References== | ==References== |
Revision as of 02:33, 13 June 2012
Squamous cell carcinoma of the skin Microchapters |
Differentiating Squamous cell carcinoma of the skin from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Squamous cell carcinoma is a locally invasive tumor that can be treated successfully in up to 95% - 98% cases with a timely management. The available options for treatment are as follows
- Cryotherapy
- Electrosurgery (curettage and electrodessication)
- Topical therapy (5-Flourouracil, photodynamic therapy, and Imiquimod for cutaneous lesions.
While systemic treatment includes
- Radiation therapy
- Surgical excision
- Mohs Microsurgery
Medical Treatment
Medical care of Squamous cell carcinoma (SCC) includes cryosurgery, electrosurgery, topical treatment for cutaneous lesions and Radiation therapy and Chemotherapy for systemic disease.
- Cryotherapy destroys malignant cells by freezing and thawing. It is useful for small, well-defined, low-risk invasive SCCs and for Bowen's disease. In cryosurgery, liquid nitrogen is applied to the tumor and a surrounding rim of normal-appearing skin (usually ≥3 mm). The frozen area is then allowed to thaw unaided. In most cases, the tumor is refrozen to complete two freeze-thaw cycles; for Bowen's disease, a single freeze-thaw cycle may be sufficient.[1].Tumor cell death is due to the formation of intra and extracellular ice crystals, hypertonicity, disruption of the phospholipid membrane, and vascular stasis. Cryotherapy is a quick procedure and is cost-effective. This therapy is not indicated for large recurrent lesions,deeply invasive and other high risk SCC.
References
de:Plattenepithelkarzinom
he:קרצינומת תאי קשקש
nl:Plaveiselcelcarcinoom