Spontaneous coronary artery dissection surgery

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Spontaneous Coronary Artery Dissection Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Spontaneous coronary artery dissection from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Approach

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Angiography

CT

MRI

Echocardiography

Other Imaging Findings

Other Diagnostic Studies

Treatment

Treatment Approach

Medical Therapy

Percutaneous Coronary Intervention

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Type 1

Type 2A

Type 2B

Type 3

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A. Arzu Kalayci, M.D. [2]

Synonyms and keywords: SCAD

Overview

Coronary artery bypass graft (CABG) is an important reperfusion therapy in selected group of SCAD patients and also a rescue strategy in the management of failed PCI.

Surgery

Emergent CABG should be considered for patients with left main dissections, extensive dissections involving proximal arteries, or in patients in whom PCI failed or who are not anatomically suitable for PCI. Although many of this operations have been performed in case of emergency, good early outcomes following CABG have been reported in small observational studies.[1] [2] [3] Early graft failure was reported as 6% in a 20 patients series. [2] [3] However long term results of CABG showed lower graft patency (27%) in a small series which is because of spontaneous arterial healing lead to competitive flow and graft thrombosis. [4]


Indications for surgical revascularization (CABG)[5] include:

  • Multivessel involvement
  • Left main coronary artery involvement
  • Progression/worsening of dissection so long as there is a distal target
  • Significant narrowing of the arterial lumen
  • Refractory or recurrent myocardial ischemia

In the event of severe refractory heart failure, heart transplantation may be considered.

References

  1. Saw J, Aymong E, Sedlak T, Buller CE, Starovoytov A, Ricci D; et al. (2014). "Spontaneous coronary artery dissection: association with predisposing arteriopathies and precipitating stressors and cardiovascular outcomes". Circ Cardiovasc Interv. 7 (5): 645–55. doi:10.1161/CIRCINTERVENTIONS.114.001760. PMID 25294399.
  2. 2.0 2.1 Tweet MS, Eleid MF, Best PJ, Lennon RJ, Lerman A, Rihal CS; et al. (2014). "Spontaneous coronary artery dissection: revascularization versus conservative therapy". Circ Cardiovasc Interv. 7 (6): 777–86. doi:10.1161/CIRCINTERVENTIONS.114.001659. PMID 25406203.
  3. 3.0 3.1 Lettieri C, Zavalloni D, Rossini R, Morici N, Ettori F, Leonzi O; et al. (2015). "Management and Long-Term Prognosis of Spontaneous Coronary Artery Dissection". Am J Cardiol. 116 (1): 66–73. doi:10.1016/j.amjcard.2015.03.039. PMID 25937347.
  4. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ; et al. (2012). "Clinical features, management, and prognosis of spontaneous coronary artery dissection". Circulation. 126 (5): 579–88. doi:10.1161/CIRCULATIONAHA.112.105718. PMID 22800851.
  5. Shamloo BK, Chintala RS, Nasur A; et al. (2010). "Spontaneous coronary artery dissection: aggressive vs. conservative therapy". The Journal of Invasive Cardiology. 22 (5): 222–8. PMID 20440039.